DT2 - GI and Lung Flashcards

1
Q

Alveolar surface area

A

143 m2

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2
Q

Capillary surface area

A

140 m2

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3
Q

90% air-blood interface surface area

A

126 m2

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4
Q

Blood content

A

0,2 L

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5
Q

How long does it take for RBC’s to pass through capillary bed?

A

0,75 seconds

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6
Q

Foveolar layer

A

mucus cells produce musus

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7
Q

Glandular layer

A

parietal cells produce acid and intrinsic factor (antrum: hormone producing cells produce gastrin)

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8
Q

Smooth muscle

A

chief cells produce pepsinogen, enterochromaffin-like cells produce histamine and hpc produce somatostatin

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9
Q

What can cause acute gastritis

A

alcohol, NSAIDS, H. pylori

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10
Q

Name types of gastritis

A

acute, lymphocytic, granulomatous, Chron’s disease, AI

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11
Q

Against which cells are antibodies produced in AI gastritis

A

parietal cells and intrinsic factor

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12
Q

Types of gastric adenocarcinoma

A

Intestinal type and diffuse type

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13
Q

Which steps leading to a gastric adenocarcinoma are genetic

A

intestinal metaplasia, dysplasia and gastric adenocarcinoma

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14
Q

Types of esophageal cancer

A

adenocarcinoma and SCC

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15
Q

Which percentage of adenoma’s progresses to CRC

A

5%

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16
Q

Advanced adenocarcinoma characteristics

A

> 10mm, high grade dysplasia, villous component

17
Q

Core business of lungs

A

Gass exchange

18
Q

Name types of surfactant producing cells

A

Type 2 pneumocytes and Type 1 pneumocytes (Clara cells)

19
Q

Which parts are part of the acinus

A

respiratory bronchiole, alveolar duct, alveolar sac, alveolus

20
Q

Which part of trachea and bronchi produce mucus

A

seromucous glands and epithelium

21
Q

Atelectasis

A

collapse

22
Q

ARDS

A

adult respiratory diffuse syndrome

23
Q

Symptoms of ARDS

A

hypoxemia, pulmonary edema, multi organ failure, acute rapidly progressive respiratory insufficiency

24
Q

Vascular diseases lungs

A

Saddle embolus, pulmonary thrombus, infarction

25
Q

Obstructive lung diseases

A

emphysema, asthma, chronic bronchitis

26
Q

emphysma

A

alveolar wall destruction, overinflation

27
Q

asthma

A

bronchial hyperresponsiveness triggered by allergens

28
Q

chronic bronchitis

A

airway inflammation

29
Q

restrictive lung disease

A

granulomatous, fibrous, eosinophilic, smoking related, mineral/dust induced

30
Q

infectious diseases

A

lobar pneumonia, bronchopneumonia, acute pneumonia

31
Q

1st Laennec stage

A

hemorrhagic exudate, pneumococci

32
Q

2nd Laennec stage

A

granulocytes, erythrocytes, fibrine, pleural effusion

33
Q

3rd Laennec stage

A

break down of erythrocytes, hemoglobine

34
Q

4th Laennec stage

A

resolution, sometimes fibrosis, bronchiectasies

35
Q

What is a hallmark of a TBC infection

A

Granuloma’s

36
Q

Is SCLC OR NSCLC more aggressive

A

SCLC

37
Q

Where is SCC in the lung usually found

A

center of lung