(DSM) Module 14- Substance-Related And Addictive Disorders Flashcards
Refers to chemical compounds that are ingested to alter mood or behavior
Substance
alters mood, behavior, or both
Psychoactive Substance
Is the ingestion of psychoactive substances in moderate amounts that does not significantly interfere with social, educational, or occupational functioning.
Substance Use
Physiological reaction to ingested substance (drunkenness, or getting high); many variables interact,
including the type of drug taken, the amount ingested, and the person’s individual biological reaction; experienced as impaired judgment, mood changes, and lowered motor ability.
Substance Intoxication
It is defined in terms of how significantly the use interferes with the user’s life which disrupts education,
job, or relationships with others, and puts one in physically dangerous situations.
Substance Use Disorder
The use of increasingly greater amounts of the drug to experience the same effect
(tolerance), and a negative physical response when the substance is no longer ingested (withdrawal)
Physiological Dependence on Drugs
Many other kinds of reinforcing experiences stimulate the release of ________, especially in the ________________, a small
subcortical area rich in dopamine
dopamine, nucleus accumbens
produces excitement, alertness, elevated mood, decreased fatigue, and sometimes increased motor activity;
directly increases activity at dopamine receptors.
Stimulants
- increases the release of dopamine from the presynaptic terminal. - reverses the dopamine transporter, causing the cell to excrete dopamine instead of reabsorbing it. - blocks certain synapses that inhibit dopamine release
Amphetamine
- blocks the reuptake of dopamine, NorE, and Serotonin, thus prolonging their effects.
Cocaine
- often prescribed for people with ADD; same mechanism as of cocaine
Methylphenidate
- a compound present in tobacco; it stimulates one type of acetylcholine receptor (nicotinic receptor) found in
CNS and nerve-muscle junction of skeletal muscles. - receptors are abundant on dopamine-releasing axon terminals in the nucleus accumbens, so it
increases dopamine in that area.
Nicotine
- major effect is to produce analgesia temporarily; include morphine, heroin and methadone, among others.
-relax people, decrease their attention-to -the-world problems, and decrease sensitivity to pain.
Opiate Drugs
- include lysergic acid diethylamide (LSD), chemically resembles serotonin. - effects include distorded sensations; alter sensory perception; produce positive psychosis
Hallucinogenic Drugs
: a cannabinoid ; relieves pain or nausea and to combat glaucoma. - psychological effects include and intensification of sensory experience and an illusion that time is passing very slowly. - cannabinoid dissolve in body’s fats and leave the body slow
Marijuana (THC)