DSA Biomolecules Flashcards
Blood Glucose Regulation and Ranges
Regulated by insulin and glucagon
- Normal fasting = 70-100 mg/dL
- Normal fed = 140
Erythritol
4C sugar used as artificial sweetener
Xylitol
- 5C alcohol used as natural sweetener
- low glycemic index
Mannitol
- Sugar alcohol used by some plants and microorganisms for energy storage
- used to treat head trauma and kidney failure
- makes BBB permeable to drugs
Sorbitol
- sugar alcohol used in chewing gum, toothpaste, mouthwash and as a laxative
Lactose Intolerance
- Body is not able to digest lactose because of a lactase deficiency.
- there is age dependent decrease in the enzyme
- results in gas, belly pain, and bloating within 2 hours of consumption
Deoxyaldolase
A component of DNA
Acetylation amino sugars
Components of glycoproteins and glycolipids
- cell signaling, cell adhesion and immuno response
Acidic sugars
Present in cell membrane and in extracellular matrix
Sugar esters
Constitute the gangliosides in oligodendrocyte of the nervous system
Sugar alcohols
Food additives, significance in uncontrolled diabetes
- cataracts and peripheral neuropathy
Isoprenoids
Synthesized from acetyl CoA via intermediate IPP
Condensation of IPP = steroids, vitamins and CoQ
Most important steroid
Cholesterol
- component of membranes
- important precursor
- vitamin D
- bile acids
- component of bile
Gallstone Correlation Box
Gallbladder stores bile
- if too much cholesterol and too little bile salts are consumed, that crystalline gallstones will form in the gallbladder.
- This can lead to malabsorption (steatorrhea) and fat soluble vitamin deficiencies.
- oral chenodeoxycholic acid can help dissolve bile stones.
Aliphatic Amino Acids
- Alanine
- Glycine
- Isoleucine
- Leucine
- Proline
- Valine