Dry Eye - what is it

Question 1

what can DED impact?

Answer 1

vision function
health status - fatigue and irritability
burden increases with DED score

Question 2

what can cause DED

Answer 2

tear film instability
reduced aqueous tear flow | increased evaporation -> tear hyperosmolarity
release inflammatory mediators
damage epithelial cell surface

Question 3

structure of tear film

Answer 3

lipid layer
aqueous layer
mucous layer
epithelium

Question 4

functions of the tear film

Answer 4

eye hydration maintenance
ocular surface lubrication
corneal nourishment
ocular surface cleanser
defends against bacterial invasion
pH buffer of ocular sources
refracts light for VA

Question 5

how would you diagnose DED using a questionnaire?

Answer 5

DEQ-5 score of 6 or more
ODSI - 13 or more

Question 6

how would you diagnose DED in clinic

Answer 6

TBUT less thsn 10
308mOsm/L in eyes
difference of 8
5 spots on cornea, 9 on conjunctiva
2mm length 25% of lid margin