Drugy drug drugs Flashcards

1
Q

Loperamide (Imodium) is used for?

A

mild to moderate diarrhea without obstruction, IBD, IBS

IBS–diarrhea dominant

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2
Q

Loperamide (Imodium) is what class?

A

Anti-diarrheal

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3
Q

Is Loperamide (Imodium) an opioid?

A

Yes

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4
Q

Is Kaolin-Pectin an opioid?

A

No

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5
Q

What class of drugs does Kaolin-Pectin belong to?

A

Anti-diarrheal

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6
Q

What is dietary fiber used for?

A

Anti-diarrheal and laxative

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7
Q

When do we use Octreotide (Sandostatin)?

A

GI bleed–diarrhea secondary to bowel dysmotility

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8
Q

Does high dose or low dose of Octerotide increase motility?

A

Low dose

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9
Q

When do we use Bismuth Subsalicylate (BSS)?

A

mild, nonspecific diarrhea, part of quadruple treatment for H. pylori

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10
Q

How do we treat severe IBD?

A

TNF antagonists, Natalizumab, Cyclosporine

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11
Q

Moderate IBD treatment?

A

Oral corticosteroids, methotrexate

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12
Q

Mild IBD treatment?

A

5-ASA, budesonide

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13
Q

Where does Sulfasalazine work in the GI tract? Osalazine? Mesalamine pH sensitive release?

A

Sulfasalazine: colon

Osalazine: colon

Mesalamine pH sensitive release: ileum

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14
Q

What is Azathioprine indicated for?

A

steroid sparing for steroid dependent Crohn’s disease, ulcerative colitis

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15
Q

What kind of drug is Infliximab (Remicade) and what is it used for?

A

Anti-TNF alfa-inflammatory agent

Indication: acute and maintenance treatment for moderate to severe Crohn’s disease and UC

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16
Q

When do we use Natalizumab?

A

It is for a subset of patients with moderate to severe Crohn’s disease who have failed other therapies

17
Q

What is our one and only gallstone medication?

A

Ursodiol

18
Q

What is Senakot (Senna) used for?

A

Constipation

19
Q

What do we use Lubiprostone (Amitiza) for?

A

Chronic idiopathic constipation

IBS-Constipation in women

20
Q

What do we use Linaclotide (Linzess) for?

A

IBS-Constipation or chronic idiopathic constipation

21
Q

How does Lubiprostone work?

A

activates calcium channels to increase bowel fluid secretion and motility

22
Q

How does Linaclotide work?

A

agonizes cGMP on luminal surface of bowel epithelium

23
Q

What do we use MiraLax for?

A

Bowel prep