Drugs working on the vasculature Flashcards
1
Q
Phenylephrine attributes
A
direct acting alpha adrenergic agonist
systemic arteriole vasoconstriction–>
- -increased systolic and diastolic pressures
- -REFLEXIVE decrease in HR and CO
2
Q
Phenylephrine administration
A
IV, IM, SC
3
Q
Phenylephrine use
A
control of hypotension, especially associated w/ regional or spinal anesthesia
4
Q
Phenylephrine adverse effects
A
angina
anxiety
hallucinations/psychosis
HTN…
5
Q
Ephedrine attributes
A
mixed-acting sympathomimetic
alpha AND beta
6
Q
Ephedrine pk
A
orally active
eliminated in urine
7
Q
Ephedrine utility
A
hypotension (esp. of analgesia)
8
Q
Ephedrine effects
A
increases:
- -HR
- -CO
- -variable increase in TPR
9
Q
Ephedrine effects
A
angina (b/c increased work load)
ventricular dysfunction
fatal arrhythmias
herbal products containing ephedra alkaloids
Precursor of illicit amphetamine and meth!!!
