Drugs to Treat Interstitial Lung Disease (Izard) Flashcards
Prednisone Cautions/warning
HPA axis suppression
Prednisone Adverse rxns (FR, AGT, EBP, WG)
fluid retention
alteration in glucose tolerance
elevation in blood pressure
weight gain
Mycophenolate class?
immunosuppressive drug
Mycophenolate indications?
RA, including patients resistant to methotrexate
prophylaxis of organ rejection in transplant patients
Mycophenolate contraindications (MA,P80)
MPA acid
pts allergic to polysorbate 80
Mycophenolate black box warning? (E,SM,L)
Embryofetal toxicity, skin malignancy, lymphoma
Mycophenolate drug interactions
Antacids with magnesium or aluminum hydroxide
PPI
Oral contraceptives efficacy may be reduced
Methotrexate usage?
life threatening neoplastic diseases
crippling psoriasis/RA.
Methotrexate black box (BMT,LT,LT,KT,P,OI)
Bone marrow, lung, liver, and kidney toxicity.
Pregnancy
Potentially fatal opportunistic infections
Methotrexate indications
Neoplastic diseases
RA
Psoriasis
Azathioprine class
immunosuppressive antimetabolite, available in tablet form for oral administration
Azathioprine indication
prevention of rejection in renal homotransplantations
Active RA.
Azathioprine contraindications (P, AA)
Pregnant women with RA
RA patient previously treated with alkylating agents
Azathioprine black box warning
Malignancy
Nintedanib indication
Kinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis
