Drugs to Treat Acute Aortic Dissection

Question 1

What is the mechanism of action of labetalol?

Answer 1

-blocks alpha and beta receptors

—>decreases peripheral vascular resistance w/o significantly altering HR or cardiac output

Question 2

What are the indications for esmolol?

Answer 2

• to control rapid HR or arrhythmias
• Tx for fast HR or HTN during and after surgery
• -good for medical procedures d/t half-life of 9mins

-watch BP closely for signs of overTx and htn

Question 3

What is a major side effect of esmolol?

Answer 3

-hyperkalemia (especially in pt’s w/ renal impairment)