Drugs That Cause Hyperglycemia Flashcards

0
Q

Asparaginase

A

BN: Elspar
MOA: inhibition of insulin synthesis
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1
Q

Alcohol

A

MOA: chronic ingestion increases tolbutamide metabolism

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2
Q

B-adrenergic antagonists

A

MOA: inhibit insulin secretion

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3
Q

Calcium channel blockers

A

MOA: inhibit insulin secretion

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4
Q

Combination oral contraceptives

A

Unknown MOA

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5
Q

Diazoxide

A

BN: hyperstat, preglycan
MOA: inhibit insulin secretion
Class: anti hypertensive (thiazide like)
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6
Q

Diuretics

A

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May be related to hypokalemia

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7
Q

Glucocorticoids

A

MOA: increase gluconeogenesis, decrease insulin action

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8
Q

Niacin

A

Unknown MOA

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9
Q

Olanzapine

A

BN: zyprexa
MOA: unknown
Class: antipsychotic
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10
Q

Pentamidine

A

BN: nebupent, Pentam
MOA: promotes pancreatic toxicity
Class: antiprotozoal
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11
Q

Phenytoin

A

BN: Dilantin
MOA: inhibits insulin secretion
Class: anti-convulsant
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12
Q

Rifampin

A

BN: rifadin
MOA: enhances metabolism of tolbutamide
Class: antitubercular
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13
Q

Sympathomimetics

A

MOA: increases gluconeogenesis and glycogenolysis

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