Drugs That Cause Hyperglycemia Flashcards
Asparaginase
BN: Elspar
MOA: inhibition of insulin synthesis
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Alcohol
MOA: chronic ingestion increases tolbutamide metabolism
B-adrenergic antagonists
MOA: inhibit insulin secretion
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Calcium channel blockers
MOA: inhibit insulin secretion
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Combination oral contraceptives
Unknown MOA
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Diazoxide
BN: hyperstat, preglycan
MOA: inhibit insulin secretion
Class: anti hypertensive (thiazide like)
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Diuretics
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May be related to hypokalemia
Glucocorticoids
MOA: increase gluconeogenesis, decrease insulin action
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Niacin
Unknown MOA
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Olanzapine
BN: zyprexa
MOA: unknown
Class: antipsychotic
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Pentamidine
BN: nebupent, Pentam
MOA: promotes pancreatic toxicity
Class: antiprotozoal
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Phenytoin
BN: Dilantin
MOA: inhibits insulin secretion
Class: anti-convulsant
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Rifampin
BN: rifadin
MOA: enhances metabolism of tolbutamide
Class: antitubercular
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Sympathomimetics
MOA: increases gluconeogenesis and glycogenolysis
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