Drugs SEM 4

Question 1

Lisinopril

Answer 1

ACE inhibitor

Question 2

Ramipril

Answer 2

ACE inhibitor

Question 3

Candesartan

Answer 3

ARB

Question 4

Losartan

Answer 4

ARB

Question 5

Amplodipine

Answer 5

CCB - Dihydropyridine

Question 6

Nifedipine

Answer 6

CCB - Dihydropyridine

Question 7

Nimodipine

Answer 7

CCB - Dihydropyridine

Question 8

Verapamil

Answer 8

CCB- Phenylalkylamines

Question 9

Diltazem

Answer 9

CCB - Benzothiazapine

Question 10

Bendroflumethiazide

Answer 10

Thiazide

Question 11

Indapamide

Answer 11

Thiazide-like

Question 12

Spironolactone

Answer 12

Aldosterone antagonist

Question 13

Labetalol- when is this used ?

Answer 13

B- Adrenoreceptor blocker

Gestational hypertension when CCBS, ACEi and ARBS contraindicated

Question 14

Bisoprolol

Answer 14

B- Adrenoreceptor blocker

Question 15

Metoprolol

Answer 15

B- Adrenoreceptor blocker

Question 16

Doxazosin

Answer 16

a adrenoreceptor blocker

Question 17

Bumetanide

Answer 17

Loop diuretic

Question 18

Furosemide

Answer 18

Loop diuretic

Question 19

Amiloride

Answer 19

Potassium sparing diuretic

Question 20

Mannitol

Answer 20

Osmotic diuretic

Question 21

Chlorothiazide

Answer 21

Thiazide

Question 22

Tolvaptan

Answer 22

ADH antagonist

Question 23

Lithium

Answer 23

Inhibits action of ADH

Question 24

Thiazides and Loop diuretics have similar ADRs what are they?

Answer 24

Gout

Increased LDL, Triacylglycerols

Question 25

Simvastatin

Answer 25

Statin

Question 26

Atorvastatin

Answer 26

Statin

Question 27

Fenofibrate- what does it do

Answer 27

Fibric acid derivative activate nuclear transcription factor- PPAR alpha which regulates expression of genes that increase production of lipoprotein lipase - decreasing TGAs and FA in LDL

Question 28

Ezetimibe

Answer 28

Cholestrol absorption inhibitors

Question 29

Alirocumab

Answer 29

PCSK9 Inhibitors

Question 30

Evolocumab

Answer 30

PCSK9 Inhibitors

Question 31

Inclisiran

Answer 31

INhibit hepatic translation of PCSK9

Question 32

Oestrogens

Answer 32

Sex steroid hormone COCP HRT

Question 33

Testosterone

Answer 33

Sex steroid hormone

Question 34

Progestrone

Answer 34

Sex steroid hormone | contraception

Question 35

Bisphosphates

Answer 35

Reduce bone turnover | Osteoporosis treatment

Question 36

Mifepristone (RU486)

Answer 36

Progesterone receptor antagonist

Question 37

Clomiphene

Answer 37

oestrogen receptor agonist

Question 38

Tamoxifen- what type of drug (metabolism)

Answer 38

Pro-drug | Selective oestrogen receptor modulator

Question 39

Ulipristal acetate

Answer 39

Selective progestrone receptor modulator