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Pharmacology > Drugs SEM 4 > Flashcards

Drugs SEM 4 Flashcards

1
Q

Lisinopril

A

ACE inhibitor

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2
Q

Ramipril

A

ACE inhibitor

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3
Q

Candesartan

A

ARB

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4
Q

Losartan

A

ARB

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5
Q

Amplodipine

A

CCB - Dihydropyridine

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6
Q

Nifedipine

A

CCB - Dihydropyridine

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7
Q

Nimodipine

A

CCB - Dihydropyridine

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8
Q

Verapamil

A

CCB- Phenylalkylamines

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9
Q

Diltazem

A

CCB - Benzothiazapine

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10
Q

Bendroflumethiazide

A

Thiazide

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11
Q

Indapamide

A

Thiazide-like

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12
Q

Spironolactone

A

Aldosterone antagonist

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13
Q

Labetalol- when is this used ?

A

B- Adrenoreceptor blocker

Gestational hypertension when CCBS, ACEi and ARBS contraindicated

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14
Q

Bisoprolol

A

B- Adrenoreceptor blocker

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15
Q

Metoprolol

A

B- Adrenoreceptor blocker

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16
Q

Doxazosin

A

a adrenoreceptor blocker

17
Q

Bumetanide

A

Loop diuretic

18
Q

Furosemide

A

Loop diuretic

19
Q

Amiloride

A

Potassium sparing diuretic

20
Q

Mannitol

A

Osmotic diuretic

21
Q

Chlorothiazide

A

Thiazide

22
Q

Tolvaptan

A

ADH antagonist

23
Q

Lithium

A

Inhibits action of ADH

24
Q

Thiazides and Loop diuretics have similar ADRs what are they?

A

Gout

Increased LDL, Triacylglycerols

25
Q

Simvastatin

A

Statin

26
Q

Atorvastatin

A

Statin

27
Q

Fenofibrate- what does it do

A

Fibric acid derivative
activate nuclear transcription factor- PPAR alpha
which regulates expression of genes that increase production of lipoprotein lipase
- decreasing TGAs and FA in LDL

28
Q

Ezetimibe

A

Cholestrol absorption inhibitors

29
Q

Alirocumab

A

PCSK9 Inhibitors

30
Q

Evolocumab

A

PCSK9 Inhibitors

31
Q

Inclisiran

A

INhibit hepatic translation of PCSK9

32
Q

Oestrogens

A

Sex steroid hormone
COCP
HRT

33
Q

Testosterone

A

Sex steroid hormone

34
Q

Progestrone

A

Sex steroid hormone

contraception

35
Q

Bisphosphates

A

Reduce bone turnover

Osteoporosis treatment

36
Q

Mifepristone (RU486)

A

Progesterone receptor antagonist

37
Q

Clomiphene

A

oestrogen receptor agonist

38
Q

Tamoxifen- what type of drug (metabolism)

A

Pro-drug

Selective oestrogen receptor modulator

39
Q

Ulipristal acetate

A

Selective progestrone receptor modulator

Pharmacology (1 decks)

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