Drugs Of Abuse- Other Depressants And All-Arounders Flashcards
What are sedatives for?
Relive tension, stress, anxiety, and irritability.
What are hypnotics? Give me some examples.
Drugs that have a sleep inducing effect such as tranquilizers, sleeping pills anti-anxiety.
What class of drug are Barbiturates under? Why?
Sedative-Hypnotic drug. Because they treat anxiety, induce sleep, control seizures.
Describe an Ultrashort acting Barbiturate? How long do they last?
Potential for abuse?
-Has a rapid onset within 1 min of IV administration.
-Lasts 15min - 3hrs.
-Rarely abused
Describe short term intermediate Barbiturates. How long does it last?
Methods of use?
Potential for abuse?
-Onset of 15 min - 40 min after oral administration. Lasts up to 6 hrs
-Capsules, tablets, liquid form, suppositories.
-Highly abusable
Describe Long-Acting Barbiturates.
What are they used for?
Abuse potential?
-Slow onset time of up to 1 hr after use.
Lasts up to 16 hrs.
-Used as sedatives, hypnotics, and anticonvulsants.
-Slow onset discourages abuse.
Physical effects of Barbiturates?
What is it similar too?
Does it have a high physical or psychological addiction potential?
-Relaxes by reducing tension and anxiety, slower reaction time, loss of motor coordination.
-Alcohol intoxication.
-Yes to both.
Barbiturate Withdrawal Symptoms?
Is medical detox necessary?
Dependence on drug life threatening?
-Anxiety, tremors, nightmares, insomnia, vomiting, and seizures.
- yes.
- yes.
What’s LD- 50?
Does it increase with tolerance? Any exemptions?
Lethal dose that would kill 50% of people who took a specific dosage for each drug.
Tolerance does increase LD-50, but NOT for Barbiturates. It remains constant.
Mixing alcohol with Barbiturates?
Death. Responsible for more overdose deaths than any combo.
What are minor tranquilizers?
Can they cause physical and/or psychological dependence?
Do they cause sedation?
-Depressant drugs used to treat anxiety and insomnia.
-yes
-no
What type of drug has the highest number of written prescriptions?
Minor tranquilizers. More than all other drug prescriptions combined.
What do low dose minor tranquilizers feel like?
Relaxes and drowsy.
What do high dose minor tranquilizers feel like?
Loss of coordination and stupor.
Describe Glutethimide? (Other sedative/hypnotics)
What can high doses do?
And overdose? Drug is often fatal
Intro in 1954 as a safe alt to Barbiturates.
Dependence potential is still as great w/ more dangerous effects.
-Result in seizures and coma
Glutethimide is combined with what drug to create the street drug called?
Combined with codeine, called loads.
Produces similar high as heroin.
Describe methaqualone (Quaalude)
Other names it goes by?
Side effects?
Overdose?
Withdrawal?
-Intro in 1965 as a safe, effective, non dependent drug to replace Barbiturates.
-toured as an aphrodisiac, sexual ability was not lost.
-Ludes, Sopors, lemons, 714’s
-loss of motor coordination, dizziness, severe hangovers.
-occasionally fatal
-needs medical supervision or death occurs.
What do Narcotics do and what are they used for?
Are narcotics naturally occurring or synthetically made?
-Cause sedation, euphoria by depressing the CNS.
-Used to relieve pain, supress cough, control diarrhea.
-Both
What is an overdose on narcotics like?
Death by respiratory depression.
What are the three classifications on Narcotics and what drugs fall in those categories?
Natural- opium, morphine, codeine.
Semi-synthetic- heroin, hydromorphone
Synthetic- Demerol, methadone, darvon.
What drug is the main source of natural occurring narcotics?
Opium
