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Drugs Indications and AE > Drugs indication and AE (1) > Flashcards

Drugs indication and AE (1) Flashcards

1
Q

Phenylephrine

A

Alpha 1 Direct adrenergic agonist for hypotension or nasal decongestion.

AE: Hypertension, reflex bradycardia

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2
Q

Brimonidine

A

Alpha 2 Direct adrenergic agonist for glaucoma

AE: Hypotension

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3
Q

Isoprenaline

A

Non selective Beta Direct adrenergic agonist for asthma or resuscitation

AE: Arrythmia, tachycardia

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4
Q

Oxymetazoline

A

Non selective alpha Direct adrenergic agonist for nasal decongestion

AE: Rebound congestion

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5
Q

Dobutamine

A

Beta 1 Direct adrenergic agonist for congestive heart failure

AE: Tachycardia

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6
Q

Salbutamol/ Terbutaline

A

Beta 2 Direct adrenergic agonist for asthma or premature labor

AE: Arrythmia, tachycardia, vasodilation

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7
Q

Mirabegron

A

Beta 3 Direct adrenergic agonist for overactive bladder. Also has slight B2/B1 effects

AE: Arrythmia, tachyardia

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8
Q

Moclobemide

A

MAO A inhibitor for depression

AE: Tachycardia, tremors

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9
Q

Reboxetine

A

Tricyclic antidepressant that acts as presynaptic uptake 1 inhibitor

AE: Insomnia

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10
Q

Ephidrine

A

Displacement of endogenous NE, acting as nasal decongestion. Also have direct alpha and beta adrenoreceptor agonist

AE: Bradycardia if systemic

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11
Q

Prazosin

A

Direct Alpha 1 anti adrenergic for hypotension or symptoms of BPH

AE: Postural hypotension, reflex tachycardia, nasal congestion, drowsiness

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12
Q

Propanolol

A

Non-selective beta anti-adrenergic for hypertension, arrythmia, excessive cathecholamine in hyperthyriod. Additional antihypertensive effect due to less renin by kidneys. Also has direct membrane effect causing local anesthetic like actions that prevent blink reflex.

AE: Bronchoconstriction, heart failure, rebound tachycardia, hypertension

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13
Q

Sotalol

A

Non-selective beta anti-adrenergic for arrythmias. Additional antihypertensive effect due to less renin by kidneys.

AE: Bronchoconstriction, heart failure, rebound tachycardia, hypertension

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14
Q

Timolol

A

Non-selective beta anti-adrenergic for glaucoma. No local anesthetic effect.

AE limited due to direct application to eyes

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15
Q

Bisoprolol

A

Selective beta 1 anti-adrenergic for hypertension, angina, MI, CHF

AE: Hypotension, bradycardia, bronchoconstriction, cold extremities, impotence, fatigue

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16
Q

Betaxolol

A

Selective beta 1 anti-adrenergic for glaucoma

Limited AE due to direct application to eyes

17
Q

Dexmedetomidine/ Clonidine

A

Agonist at pre-synaptic alpha 2 adrenergic auto-receptors (feedback inhibition of NE release, leading to less visceral vasoconstriction). Used as sedative/ centrally acting hypertension

AE: hypotension, dry mouth

18
Q

Methyldopa

A

Inhibits tyrosine kinase, used for hypertension in pregnancy.

AE: hemolytic anemia, hepatotoxicity

Drugs Indications and AE (2 decks)

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