Drugs in health and disease Flashcards
Describe the lock and key mechanism of drug action
Drug and receptor form a drug receptor complex
This leads to a response
What are the doses in the BNF?
Licensed
What are unlicensed doses?
Any higher than the ones in the BNF
What do side effects of the drug relate to?
The drugs mechanism of action
How do you prescribe for the elderly?
Risk benefit
Prescribe lower doses
Blockade of dopamine D2 receptors leads to what symptoms?
Extrapyramidal
Blockade of cholinergic receptors leads to what symptoms?
Antuimuscarinic
Blockade of alpha adrenergic receptors leads to what symptoms?
Nasal congestion
ED
Blockade of histaminergic receptors leads to what main symptom?
Drowsiness
Blockage of serotonergic receptors leads to what main symptom?
Hypotension
Interference with temperature regulation