Drugs in health and disease Flashcards

1
Q

Describe the lock and key mechanism of drug action

A

Drug and receptor form a drug receptor complex

This leads to a response

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2
Q

What are the doses in the BNF?

A

Licensed

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3
Q

What are unlicensed doses?

A

Any higher than the ones in the BNF

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4
Q

What do side effects of the drug relate to?

A

The drugs mechanism of action

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5
Q

How do you prescribe for the elderly?

A

Risk benefit

Prescribe lower doses

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6
Q

Blockade of dopamine D2 receptors leads to what symptoms?

A

Extrapyramidal

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7
Q

Blockade of cholinergic receptors leads to what symptoms?

A

Antuimuscarinic

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8
Q

Blockade of alpha adrenergic receptors leads to what symptoms?

A

Nasal congestion

ED

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9
Q

Blockade of histaminergic receptors leads to what main symptom?

A

Drowsiness

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10
Q

Blockage of serotonergic receptors leads to what main symptom?

A

Hypotension

Interference with temperature regulation

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