Drugs for tachyarrhythmia management- RANDOM

Question 1

What is the effect of beta blockers?

Answer 1

Slows AV nodal conduction > slows ventricular response rate > decreases contractility

Reduces myocardial oxygen demand

Question 2

What type of drug is Lidocaine (IV)?

Answer 2

Class Ib Na+ channel blocker

Question 3

What type of drug is Propranolol?

Answer 3

Class II beta-adrenergic receptor blocker

Question 4

What type of drug is Sotalol?

Answer 4

Class III K+ channel blocker

Question 5

What type of drug is Mexiletine (PO)?

Answer 5

Class Ib Na+ channel blocker

Question 6

What drugs would you use for ventricular tachyarrhythmia?

Answer 6

Na+ channel blockers, K+ channel blockers, beta blockers

Question 7

What is the side effect of using K+ channel blockers?

Answer 7

1. Sotalol: negative inotrope

Bradycardia and prolonged QT in humans

Question 8

What is the side effect of using class Ia Na+ channel blockers?

Answer 8

1. GI effects

2. Quinidine: increases digoxin levels

Question 9

What type of drug is Metoprolol?

Answer 9

Class II beta-adrenergic receptor blocker

Question 10

What is the effect of Ca++ channel blockers?

Answer 10

Blocks L-type calcium channel > decreases ventricular response rate by slowing AV nodal conduction (interrupt re-entry)

Also works on SA node

Question 11

What is the side effect of using class Ib Na+ channel blockers?

Answer 11

1. CNS effects (depression, seizures)

2. CAUTION IN CATS! (glucuronide; have to give 1/10th - 1/20th dose)

Question 12

What drugs would you use for supraventricular arrhythmia (A-fib, SVT)?

Answer 12

Class Ia Na+ channel blockers, beta blockers, Ca++ channel blockers

Question 13

What type of drug is Quinidine?

Answer 13

Class Ia Na+ channel blocker

Question 14

What is the effect of K+ channel blockers?

Answer 14

Prolongs AP and refractory period (interrupt re-entry)

Question 15

What is used prophylactically for ventricular arrhythmias in semilunar valve stenosis?

Answer 15

Beta blockers

Question 16

What is the effect of class Ia Na+ channel blockers?

Answer 16

Prolongs AP duration (atrial and ventricular cells)

Question 17

What is the effect of class Ib Na+ channel blockers?

Answer 17

Shortens AP duration (ventricular cells primarily)

Question 18

What type of drug is Atenolol?

Answer 18

Class II beta-adrenergic receptor blocker

Question 19

What is the first line for ventricular arrhythmia in cats?

Answer 19

Beta blockers (Atenolol, Esmolol)

Question 20

What type of drug is Amiodarone?

Answer 20

Class III K+ channel blocker

Question 21

What type of drug is Procainamide?

Answer 21

Class Ia Na+ channel blocker

Question 22

What is used to treat life-threatening ventricular tachycardia?

Answer 22

Lidocaine

Question 23

What type of drug is Diltiazem (IV and PO)?

Answer 23

Class IV Ca++ channel blocker

Question 24

What type of drug is Esmolol?

Answer 24

Class II beta-adrenergic receptor blocker

Question 25

What is the side effect of using Ca++ channel blockers?

Answer 25

1. Negative inotrope
2. Bradycardia
3. AV block
4. GI upset (cats don’t deal with this well)

Question 26

What is the side effect of using beta blockers?

Answer 26

1. Negative inotrope
2. Ngative chronotrope
3. Worsening of asthma (cats)