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Pharm Chapter 14 > Drugs For Pain Control > Flashcards

Drugs For Pain Control Flashcards

(78 cards)

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1
Q

Nociceptor

A

Activation of receptor nerve endings that receive and transmit pain signals to the spinal cord and brain

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2
Q

Endogenous opioids

A

Group of neurotransmitters including endorphins, dynorphins, and enkephalins

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3
Q

Analgesics

A

Medications used to relieve pain

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4
Q

Opioid

A

Narcotic which is a Natural or synthetic morphine like substance responsible for reducing severe pain, produces numbness or stuporlike symptoms.

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5
Q

Opiates

A

Opium consisting of 9% to 14% morphine and 0.8 to 2.5% codeine

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6
Q

Narcotic

A

Stupor associated with morphine like drugs that produce analgesia and CNS depression.

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7
Q

Codeine

A

Opioids for pain management
Opioid agonists with Moderate effectiveness

Also for cough; avail in IM and SC forms; combination drug with aspirin is called empirin with codeine and with acetaminophen, tylenol with codeine

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8
Q

Hydrocodone bitartrate (bi-tar-trate) (hycodan)

A

Opioids for pain management
Opioid agonists with Moderate effectiveness

Also for cough; combination drug with acetaminophen is called amacodone C, Co-Gesic, Vicodin, Dolacet, Norcet, and Norco

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9
Q

Oxycodone hydrochloride (OxyContin)

Oxycodone terephthalate (Percocet-5, Roxicet, others)

A

Opioids for pain management
Opioid agonists with Moderate effectiveness

Combination drug with acetaminophen is called Percocet or Tylox; with aspirin is called Percodan or Roxiprin

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10
Q

Propoxyphene hydrochloride (Darvon)

Propoxyphene napsylate (Darvon-N)

A

Opioids for pain management
Opioid agonists with Moderate effectiveness

Combination drug with acetaminophen is called Darvocet or Propacet; with aspirin and caffeine is called Darvon or Dolene

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11
Q

Fentanyl (Sublimaze)

A

Opioids for pain management
Opioid agonists with High effectiveness

Used with anesthesia for surgery and other procedures

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12
Q

Hydromorphone hydrochloride (Dilaudid)

A

Opioids for pain management
Opioid agonists with High effectiveness

Also for cough; avail IM, IV, SC, and rectally

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13
Q

Levorphanol tartrate (Levo-Dromoran)

A

Opioids for pain management
Opioid agonists with High effectiveness

Also avail in SC forms

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14
Q

Meperidine hydrochloride (Demerol)

A

Opioids for pain management
Opioid agonists with High effectiveness

For Preoperative rx or obstetric analgesia; avail in IM, IV, and SC forms

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15
Q

Methadone hydrochloride (Dolophine)

A

Opioids for pain management
Opioid agonists with High effectiveness

For detox treatment of opioid dependency; avail IM and IV forms

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16
Q

Morphine sulfate (Astramorph PF, Duramorph, others)

A

Opioids for pain management
Opioid agonists with High effectiveness

Avail IM, IV, SC, Intrathecal, epidural, and rectal forms

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17
Q

Oxymorphone hydrochloride (Numorphan)

A

Opioids for pain management
Opioid agonists with High effectiveness

Also avail in IV and rectal forms

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18
Q

Nalmefene hydrochloride (Revex)

A

Opioids for pain management
Opioid antagonist

For opioid overdose and postoperative opioid depression

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19
Q

Naloxone (Narcan)

A

Opioids for pain management
Opioid antagonist

For opioid overdose and postoperative opioid depression

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20
Q

Naltrexone hydrochloride (Trexan, ReVia)

A

Opioids for pain management
Opioid antagonist

For management of opiate or alcohol dependence; longer lasting effect than naloxone

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21
Q

Buprenorphine hydrochloride (Buprenex)

A

Opioid for pain management
Opioid with mixed agonist- antagonist effects

For moderate to severe pain; also avail SC, epidural, and rectally

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22
Q

Butorphanol tartrate (Stadol)

A

Opioid for pain management
Opioid with mixed agonist- antagonist effects

For obstetrical analgesia during labor, cancer pain, renal colic, and burns; avail in IV and intranasal forms

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23
Q

Dezocine (Dalgan)

A

Opioid for pain management
Opioid with mixed agonist- antagonist effects

Causes less respiratory depression than morphine sulfate

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24
Q

Nalbuphine hydrochloride (Nubain)

A

Opioid for pain management
Opioid with mixed agonist- antagonist effects

For moderate to severe pain

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25
Pentazocine hydrochloride (Talwin)
Opioid for pain management Opioid with mixed agonist- antagonist effects For moderate to severe pain ( lower dose fir women in labor)
26
Patient controlled analgesia (PCA)
Pts are allowed to self medicate with opiate rx by pressing a button, safe levels of pain rx are delivered with an infusion pump
27
Cyclooxygenase (COX)
Enzyme responsible for the formation of prostaglandins
28
Acetaminophen (Tylenol)
Nonopioid analgesics Also for fever; avail in rectal form
29
Celecoxib (Celebrex)
Nonopioid analgesics NSAID selective COX-2 inhibitor Also for inflammation
30
Diclofenac (Cataflam, Voltaren)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
31
Diflunisal (Dolobid)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
32
Etodolac (Lodine)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
33
Fenoprofen calcium (Nalfron)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
34
Flurbiprofen (Ansaid)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Similar to ibuprofen
35
Ibuprofen (advil, motrin)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for fever and inflammation
36
Indomethacin (Indocin)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also used for moderate to severe rheumatoid arthritis and acute gouty arthritis
37
Ketoprofen (Actron, Orudis)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
38
Ketorolac tromethamine (Toradol)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for allergic conjunctivitis, avail in IM/IV forms
39
Mefenamic acid (Ponstel)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Used for short-term relief of mild to moderate pain, incl. menstrual cramps
40
Meloxicam (mobic)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Used for osteoarthritis
41
Nabumetone (Relafen)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Inhibits COX-2 more than COX-1
42
Naproxen (Naprosyn)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
43
Naproxen sodium (Aleve, anaprox)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for dysmenorrhea
44
Oxaprozin (Daypro)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Similar to naproxen; once a day dosage
45
Piroxicam (feldene)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Has prolonged half-life
46
Sulindac (Clinoril)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
47
Tolmetin (tolectin)
Nonopioid analgesics Ibuprofen and ibuprofen-like: nonsalicylates Also for inflammation
48
Aspirin (acetylsalicylic acid, ASA)
Nonopioid analgesics Salicylate Also for fever, inflammation, and thromboembolic disorders, prevention of TIA and heart attacks; avail rectally
49
Choline salicylate (Arthropan)
Nonopioid analgesics Salicylate Also for inflammation; may be indicated for pts having difficulty swallowing tablets or capsules
50
Salsalate (Disalcid)
Nonopioid analgesics Salicylate Also for fever, inflammation
51
Clonidine (Catapres)
Nonopioid analgesics Centrally acting drug Also used for hypertension
52
Tramadol (Ultram)
Nonopioid analgesics Centrally acting drug Causes less respiratory depression than morphine
53
Ziconotide (Prialt)
Nonopioid analgesics Centrally acting drug Also used for muscle spasticity
54
A fibers
Wrapped thinly in myelin that signal sharp, well defined pain
55
C fibers
Unmyelinated and conduct dull, poorly localized pain
56
Dihydroergotamine mesylate
Antimigraine drugs Drugs for terminating migraines Ergot alkaloids Also avail as nasal spray; preg category X, may be used in combination with low-dose heparin to prevent postop DVT
57
Ergotamine tartrate (Ergostat)
Antimigraine drugs Drugs for terminating migraines Ergot alkaloids Also avail. In sublingual, inhalant, or rectally; may cause physical dependence; pregnancy category X
58
Almotriptan (Axert)
Antimigraine drugs Drugs for terminating migraines Triptans May cause heart palpitations and rapid heartbeat
59
Eletriptan (Relpax)
Antimigraine drugs Drugs for terminating migraines Triptans May cause hypotension in elderly pts
60
Frovatriptan (Frova)
Antimigraine drugs Drugs for terminating migraines Triptans May cause chest pains and heart palpitations
61
Naratriptan (Amerge)
Antimigraine drugs Drugs for terminating migraines Triptans Serotonin stimulator
62
Rizatriptan (Maxalt)
Antimigraine drugs Drugs for terminating migraines Triptans May cause MI
63
Sumatriptan (Imitrex)
Antimigraine drugs Drugs for terminating migraines Triptans Serotonin stimulator; subcutaneous and intranasal forms avail.
64
Zolmitriptan (Zomig)
Antimigraine drugs Drugs for terminating migraines Triptans Serotonin stimulator
65
Topiramate (Topamax)
Antimigraine drugs Drugs for preventing migraines Antiseizure Drugs Sugar-like chemical molecule; enhances the action of GABA; also for partial seizures
66
Valproic acid (Depakene)
Antimigraine drugs Drugs for preventing migraines Antiseizure Drugs Also for absence seizures and mixed generalized types of seizures and mania
67
Atenolol (Tenormin)
Antimigraine Drugs Drugs for preventing migraines Beta-Adrenergic Blockers Also used for hypertension and angina
68
Metoprolol (Lopressor)
Antimigraine Drugs Drugs for preventing migraines Beta-Adrenergic Blockers Also for angina and MI; sustained-release and IV forms avail.
69
Proranolol (Inderal,InnoPran XL)
Antimigraine Drugs Drugs for preventing migraines Beta-Adrenergic Blockers
70
Timolol (Blocadren)
Antimigraine Drugs Drugs for preventing migraines Beta-Adrenergic Blockers Also for hypertension, angina, and glaucoma
71
Nifedipine (Adalat, Procardia)
Antimigraine Drugs Drugs for preventing migraines Calcium Channel Blockers Selective for calcium channels in blood vessels; decreases peripheral vascular resistance and increases cardiac output; also for hypertension and angina; sustained-release form avail.
72
Nimodipine (Nimotop)
Antimigraine Drugs Drugs for preventing migraines Calcium Channel Blockers Offlabeled use for migraines; primary use is for improvement of neurologic symptoms following a stroke
73
Verapamil (Calan, Isoptin, others)
Antimigraine Drugs Drugs for preventing migraines Calcium Channel Blockers
74
Amitriptyline hydrochloride (Elavil)
Antimigraine Drugs Drugs for preventing migraines Tricyclic Antidepressants
75
Imipramine (Tofranil)
Antimigraine Drugs Drugs for preventing migraines Tricyclic Antidepressants May cause cardiac dysfunction and abnormal blood cell count; also for alcohol or cocaine dependence; may control bedwetting in children; avail IM
76
Protriptyline (Vivactil)
Antimigraine Drugs Drugs for preventing migraines Tricyclic Antidepressants For symptoms of depression; few sedative qualities; causes increased heart rate
77
Methysergide (Sansert)
Antimigraine Drugs Drugs for preventing migraines Misc. drugs Similar to ergotamine
78
Riboflavin (vitamin b2)
Antimigraine Drugs Drugs for preventing migraines Misc. drugs Deficiency caused by chronic diarrhea, liver disease, alcoholism, or inadequate consumption of milk or animal products

Pharm Chapter 14 (1 decks)

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