Drugs for OR Flashcards
T: Ancef G: cefazolin
A: Bactericidal. S/D: 500mg-1g q6-8 hr for 24 hr s/p surgery. S/E: pain, phlebitis, stevens-johnsons syndrom, N/V, diarrheam, rash pseudomembranous colitits. N/I: Observer for anaphylaxis, monitor bowel function, assess for rash. R: Preoperative prophylazis
T: ativan G: Lorazepam
A: depresesses the CNS via potentiating GABA.S/D: 44mcg/kg (do not exceed 2 mg) IV. S/E: dizziness, drowsiness, lethargy, forgetfulness. N/I: Do not exceed 2mg /min, R: decrases preoperative anxiety and procvides amenesia
T: Atr-Pen G: Atropine
A:Inhibits achetylcholine at postganglionci sites in smooth muscle. S/D:0.4 mg-0.6mg 30-60 min pre-op. S/E: drowsiness, blurred vision, tachcardia, urinary hesitancy.N/I: monitor v/s, ECG, I&O, assess bowel sounds. R: Given IM peroperiatlively to reduce oral & respiratory secretions.
T: Benadryl G: Diphenhydramine
A: andgionizes the effects of histamine, CNS depressant & anticholinergic properties. S/D: 25-50 mg q 4-6hr do not exceed 300mg/day. S/E: drowsiness, anorexia, dry mouth. N/I: assess for urticaria, airway patentcy, R: Relief of allergic symptoms caused by histamine.
T: Rocephin G: Cefotaximine
A: Bacterialcidal S/D: 1g 30-90 min before incision. S/E: pain, phlebitis, stevens-johnsons syndrom, N/V, diarrheam, rash pseudomembranous colitits. N/I: Observer for anaphylaxis, monitor bowel function, assess for rash. R: Preoperative prophylaxis
T: Ceftin G: cefuroxime
A: Bacterialcidal S/D: 1.5 g IV 30-60 min before incision. S/E: pain, phlebitis, stevens-johnsons syndrom, N/V, diarrheam, rash pseudomembranous colitits. N/I: Observer for anaphylaxis, monitor bowel function, assess for rash. R: Preoperative prophylazis
T: Demerol G: meperidine
A: binds to opiate receptors in the CNS. Alters preception and respones to painful stimuli, while producing generalized CNS dpression.S/D: 50-100mg IM or SQ 30-90 prior to anesthesia. S/E: confusion, sedation, hypotension, consitpaiton, N/V, seizure, respiratory depression. N/I:Monirot V/S, LOC changes, bowel changes. R: Preoperative sedation
T: Dilaudid G: Hydromorphone
A: binds to opiate receptors in the CNS. Alters preception and respones to painful stimuli, while producing generalized CNS dpression. S/D: Dose depends on pain and drug tolerance. Start with 1.5mg q3-4 hr. S/E: confusion, sedation, hypotension, consitpaiton, N/V, seizure, respiratory depression. N/I:Monirot V/S, LOC changes, bowel changes. R: Preoperative sedation
T: Cardizem G: Diltiazem
A: Inhibits transoport of Ca into mycarial and vascural smoothe muscle cells. S/D: 0.25 mg/kg q15 min with 0.35mg/kg S/E: peripheral edema, arrhythmias, HF, stevens-johnson syndrome. N/I:Montior V/S, record ECG, monirot I&O, assess for rash R: Treat arrhythmias like SVT, A-fib, also treats HTN.
T: Dobutex G: Dobutamine
A: stimulates beta 1 aderenrgic receptors with relatively minor effect on the heart or peripherial blood vessesls. S/D: 2.5 -15mg/kg/min tirated to respones (up to 40mcg/kg/min) S/E: hypertension, increased HR, PVCs, SOB. N/I: Monitro V/S, palpate peripheral pules. R: Short term management of heart failure caused by surgical procedures.
T: Inropin G: dopamine
A: Depends on the dose- low produces renal vasodialation, large stimulates beta 1 adernergic receptors, producing cardiac stimuation and reneal vasodialaion.S/D: Beta effects 5-15 mcg/kg/min. S/E: arrhythmias, hypotesion (low dose) dyspnea, irrtation at IV site. N/I: Monitor V/S, I&O, for extravassaiton d/t necrotic effects. R: Increases cardiac output, increases BP and improves renal blood flow. R
T: Sublimaze G: fentanyl
A: binds to opiate receptor sites in the CNS, altering the response to & preception of pain. Produces CNS depression.S/D: 50-100 mcg/ kg (up to 150 mcg/kg) S/E: apnea, larygeospasm, bradicardia, hypotension. N/I: monior v/s esp EtCO2. R: preoperative & postoperative analgesia. Supplement to regional/ local analgesia.
T: Flagyl G: metronidzole
A: Bactericidal. S/D: 15mg/kg 1 hr before surgery, then 7.5mg/kg 6-12 hr later. S/E: dizziness, HA, aseptic meningitis, encephalpathy, abdominal pain, anorexia, nausea, steven johnsons syndrome, seizues. N/I: Assess for infection, rash. Montior I& O and neurological status. R: perioperative prohylactic agent in colorectal surgery.
T: Cidomycin G: gentamicin
A: bactericidal.S/D: 1-2 m/kg q8 hr (up to 6mg/kg/day in 3 doses) S/E: ataxiam, otoxicity, nephrotoxicity, sinusitis. N/I: monitor kiney function, monitor 8th crainal nerve function. R: Preventin of infective endocarditis
T: Hepalean G:Heparin
A: inhibits effectof antithrombin on factor Xa. S/D: 10,000 units followed by 5000-10000 units q4-6 hr. S/E: bleeding, heparin induced thrombocytopenia. N/I: Assess for signs of hemorrhage, thrombosis. Monitor labs Parital thromboplastin time (PTT) R: prophylaxis to prevent thromboembolic.
T: Inapsine G: droperidol
A: alters the action of dopamine in the CNS.S/D: 2.5mg initally with 1.25mg for the second dose S/E: extrapyramidal rxns, seizure, changes in mental status, arrhythmias, hpotensin, tachycardia. N/I: Assess for N/V & bowel sounds, assess for extrapyramidal rxns. Monitor V/S R: used to decrease postoperative N/V