Drugs for Leprosy

Question 1

Drugs

Answer 1

RIFAMPICIN
RIFABUTIN
DAPSONE
CLOFAZIMINE
ETHAMBUTOL

Question 2

M.avium, M.intracellulare

Answer 2

common cause of opportunistic infections (eg AIDS)

USE: ETHAMBUTOL + macrolide(prophylaxis when CD4 count <50)

Question 3

inducers of CYP450

Answer 3

both RIFAMPICIN & RIFABUTIN

Question 4

M.leprae

Answer 4

DAPSONE (SE: agranulocytosis, hemolytic anaemia due to G6PD def.)
RIFAMPICIN (treat leprosy caused by M.leprae)
CLOFAMIZINE (treat lepromatus leprosy)