Drugs For Coagulating Disorder Flashcards
What are the classification of drugs in coagulation disorder
Antithrombics
Prothrombics
What are the types of antithrombics
Anticoagulants
Antiplatelets
Fibrinolytics
What are the types of prothrombics
Vitamin K
Epsilon-Aminocaproic Acid
What is the physiology of clot formation
Stimuli of clot formation
Protein and cellular events in clot formation
What are the different types of stimuli clot formation
Endothelial injury
Blood stasis
Prescence of foreign substance
What are the diffract types of protein and cellular events in clot formation
Platelet migration and aggregation
Activation of coagulation cascade
In platelet migration and aggregation what are the 2 subtypes
Pro aggregants
Anti aggregants
Pro-aggregants should promote..?
Clot
What are the different types of drugs in pro aggregants
TXA2
5-HT
ADP
What are the different types of drugs in anti aggregants
PGI2
PGE2
cAMP
What are the receptors dor platelet migration and aggregation
GPIa
GPIb
GPIIb/IIIa
GPIa bind to platelets to
Collgen
GPIb binding of platelets to..
Von willebrand factor
GPIIb/IIIa for??
Interplatelet binding (through fibrinogen)
What is the product in platelet migration and aggregation
Platelet plug / primary hemostasis white thrombus