Drugs contraindicated in pregnancy

Question 1

Category X Drugs: avoid in pregnant patients

Answer 1

• Vitamin A and its derivatives: Accutane, acitretin (Soriatane), etretinate (Tegison)
• thalidomide
• diethylstilbesterol
• warfarin
• Danazol
• statins
• finasteride/dutasteride
• testosterone
• oral contraceptives
• methotrexate
• ACE inhibitors- growth retardation, birth defects, fetal death
• lithium- affects fetal thyroid, heart causing other abnormalities
• phenytoin- cleft lip/palate
• anticonvulsants- trimethadione, valproic acid, carbamazepine
• androgens- multiple defects