drugs autonomic Flashcards
purpose of drugs
mimic or antagonize autonomic effects
agonists
mimetics
antagonist
blockers
beta blockers
metaprolol
- blcks NE binding of B1 receptor
- decreases heart rate and contractility to treat hypertension
beta agonist
albuterol
- mimics NE to stimulate B2
- increases bronchodilation in asthma or COPD (by opening airway diameter)
alpha antagonists
prazosin
- blocks A1 receptors in blood vessels to relax smooth and treat hypertension
alpha agonists
brimonidine
- stimulates A2 receptors to reduce aqueous humor secretion and intraocular pressure in glaucoma
antimuscaranics/anticholinergic
blocks acetylcholine binding
topicamide
(antimuscarinic)
cause pupil dilation for retina check
solifenacin
(antimuscarnic)
reduces bladder sphincter relaxation for incontinence
muscarinics/cholinergics
mimics ACH or increases release
cisapride
(muscarinic)
increase GI motility for constipation