Drugs and testing

Question 1

What are the 3 stages of drug testing?

Answer 1

Preclinical
Animal trials
Human clinical trials

Question 2

What happens in preclinical trials?

Answer 2

Drugs are tested on human cells grown in labs, this allows efficacy and possible side effects to be tested

Question 3

What happens in animal trials?

Answer 3

Animals are given a known amount of substance to the animal then monitor them carefully for side effects

Question 4

What happens in the the 1st stage of human trials?

Answer 4

Range of doses is used on a small amount of participants to see if the drug is safe to use

Question 5

What happens in the 2nd stage of human trials?

Answer 5

Tested on a small group of patients to test efficacy

Question 6

What happens in the 3rd stage of human trials?

Answer 6

-Drug is given to a large group of participants to test efficacy and side effects
-Double blind trial

Question 7

Explain Withering’s digitalis soup experiment

Answer 7

He isolated the active ingredient from foxglove and then tested different doses on patients and recorded the findings, led to the development of contemporary drug testing protocols.

Question 8

Explain why placebos are used to test the efficacy of new drug treatments

Answer 8

-Can be used as a comparative to see how effective a new drug actually is
-You can clearly see the effect of the new drug
-No psychological effect