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VPharma 102 > Drugs Acting on the GIT > Flashcards

Drugs Acting on the GIT Flashcards

1
Q

group of drugs to promote vomiting

A

emetics

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2
Q

emetic of choice for dogs

A

apomorphine

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3
Q

induces vomiting in cats

A

xylazine

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4
Q

example of peripheral acting emetic

A

hydrogen peroxide

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5
Q

group of drugs used to control vomiting

A

antiemetics

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6
Q

drugs that control the chemoreceptor trigger zone and CNS control of emesis used as antiemetics for apomorphine and xylazine

A

CHLORPROzine, PROCHLORPERAzine, PROMETHAzine

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7
Q

antihistamine, used for preventing motion sickness induced vomiting in cats and dogs

A

Diphenhydramine, Dimenhydrinate, Meclizine

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8
Q

5-HT3 receptor antagonists, tx for severe nausea caused by chemotherapy, chemoreceptor trigger zone (CRTZ) and vagal nerve stimulation center

A

DOLAsetron, GRANIsetron, ONDANsetron

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9
Q

neurokinin (NK1) receptor antagonist, stops vomiting centers

A

Maropitant

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10
Q

GI prokinetic agent, stimulates upper GI motility to reduce vomiting

A

Metoclopramide

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11
Q

histamine is secreted by

A

Enterochromaffin like cells

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12
Q

chief cells secrete

A

pepsinogen, gastric lipase, leptin

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13
Q

D cells secrete

A

somatostatin

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14
Q

produce ghrelin, obestatin, serotonin abd atrial natriutic peptide

A

enterochromaffin cells

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15
Q

produce mucus and bicarbonate

A

mucous cells

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16
Q

secrete gastrin

A

G cells

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17
Q

ions secreted at the basal side of the parietal cells in exchange to chloride

A

Bicarbonate ions

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18
Q

used as treatment for GI ulcers/erosion

A

Omeprazole

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19
Q

proton-pump inhibitor with similar effect to famitidine (?) and/or omeprazole, but omeprazole is considered to be more effective

A

Pantoprazole

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20
Q

secretion of histamine are reduced by

A

somatostatin and prostaglandins

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21
Q

primary trigger for histamine release from the enterochromaffin-like cells

A

gastrin

22
Q

inhibits histamine release

A

somatostatin, calcitonin-gene related peptide (CGRP), peptide YY, prostaglandins, galanin

23
Q

secretion of histamine is increased by

A

gastrin, aspirin, indomethacin

24
Q

prototype H2 blocker

A

Cimetidine

25
Q

a gastromucosal protectant, locally-acting treatment for GI ulcers, treatment of oral, esophageal, gastric, and duodenal ulcers

A

sucralfate

26
Q

a prostaglandin e analog, used for treating/preventing gastric ulcers

A

misoprostol

27
Q

appetite stimulant for cats

A

cyproheptadine

28
Q

appetite stimulant for dogs

A

diazepam

29
Q

used as appetite stimulant and antiemetic in dogs and cats

A

mitrazapine

30
Q

appetite stimulant for cats, treat behavioral prob in cats and dogs

A

oxazepam

31
Q

drugs that increase motility of the GI smooth muscle without acting as a purgative

A

GI stimulant

32
Q

oral GI prokinetic agent, used in several species for GI stasis, reflux esophagitis, constipation/megacolon

A

Cisapride and domperidone

33
Q

suggested for use in intestinal atony or distention

A

dexpanthenol

34
Q

indicated for rumen atony, initiate persitalsiss, emptying the bladder and stimulating skeletal muscle contractions

A

neostigmine

35
Q

pancreatic enzyme used to treat exocrine pancreatic enzyme deficiency

A

pancrealipase

36
Q

group of drugs used to increase bowel movement by loosening the stool

A

laxatives

37
Q

disccharide laxative and reducer of ammonia blood levels

A

lactulose

38
Q

surfactant , stool softener

A

docusate

39
Q

an osmotic laxative

A

glycerin (suppository)

40
Q

lubricant llaxative, usually used for horses

A

mineral oil

41
Q

laxative of choice for sand colic in horses

A

psyllium

42
Q

class of drug used to treat acute and chronic diarrhea

A

antidiarrheals

43
Q

a central a2 agonist, used as an adjunctive treatment in patients with inflammatory bowel disease

A

clonidine

44
Q

opiate agonist, anticholinergic. combined for antidiarrheal prod in dogs

A

Diphenoxylate and Atropine

45
Q

GI adsorbent/protectant

A

Kaolin/Pectin

46
Q

synthetic opiate GI motility modifier

A

loperamide

47
Q

opiate GI modifier, used as motility modifier for animals w/ diarrhea, not used in cats

A

Paregoric

48
Q

used as treatment for abdominal visceral spasm, pylorospasm or hypertrophic gastritis and associated nausea, vomiting and/or diarrhea for use in dogs and cats

A

aminopentamide and hyoscyamine

49
Q

injectable anticholinergic used in treating colic

A

N-butylscopolammonium Br

50
Q

quaternary antimuscarinic agent used for its antispasmodic/antisecretory for treatment of diarrhea, hyper reflaxic detrusor or urge incontinence and anticholinergic responsive bradycardias

A

propantheline

VPharma 102 (1 decks)

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