Drugs Flashcards
What is Aciclovir for?
Anti Herpes
It’s a nucleoside analogue
Has low toxicity
What is Valaciclovir and Famciclovir for?
For Herpes and Shingles
What is Valganciclovir for?
Herpes
It may cause Bone marrow toxicity
It is a prodrug of Ganciclovir
What is Codofovir for?
Herpes, Retinitis (if there’s no other drug option)
What is Foscarnet for?
Herpes,
It very Nephrotoxic
How to treat HIV?
State an example for each.
At least 3 combination of drugs
-2 Nucleoside analogue reverse transcriptase inhibitor = Zidovudine
+ either
-Non-nucleoside reverse transcriptase inhibitor = Nevirapine
Or
-Viral Protease inhibitor = Saquinavir
What is Interferon-a for?
Chronic Hep B,C
It can be give orally.
What’s Adefovir dipivoxil and Lamivudine for?
Chronic Hep B,C
Lamivudine is mainly for HIV, but with Adefovir Dipivoxil also suitable for selected patient with HepB
What is Zanamivir and Oseltmivir for?
- Viral Respiratory infection
- Treatment of influenza A,B (within 48hours of the onset of symptoms)
- Also for Post-exposure prophylaxis
What is Ribavirin for?
For Viral Respiratory Infection
For severe Respiratory Syncytial Virus (RSV)
And
Hep C
What is Remdesivir for?
COVID
What are the 4 main types of Anti-fungal drugs? What are their functions?
Polyenes: binds to Ergosterol, increase permeability
Azoles: Prevent Ergosterol production
Allyamines: Also prevent Ergosterol production, just acts a bit earlier than Azoles
Echinocandins: prevent production of glucans
State 2 examples of Polyenes
Amphoteric B: the only IV drug for systemic fungal infection. Extremely Toxic (like your ex)
Nystatin: topical use only
States some examples for Azoles
Literally just anything that ends with azole. I know right ?! Your welcome
Recent Triazoles
Itraconazole, Voricanazole, Fluconazole
(Mnemonics: IVF)
Example of Allylamine?
Terbinafine (ends with ine like Allylamine)
