Drugs Flashcards

1
Q

Methotrexate

A

Antimetabolite

  • Crohns
  • RA
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2
Q

Allopurinol

A

Xanthine oxidase inhibitor

-gout

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3
Q

Prochlorperazine

A

Antiemetic/ FGA

  • schizophrenia
  • mania
  • anxiety
  • nausea/ vom
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4
Q

Bendroflumethazide

A

Thiazide diuretic

  • oedema
  • HTN
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5
Q

Oxybutynin

A

Antimuscarninic

-urinary incontinence

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6
Q

Tamoxifen

A

Antioestrogen

  • Breast cancer
  • anovulatory infertility
  • gynaecomastia in males
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7
Q

Chlorphenamine

A

Antihistamine

  • hay fever
  • chicken pox itch
  • urticaria
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8
Q

Azathioprine

A

Immunosuppressant

  • UC
  • Crohns
  • 2nd line: In myasthenia gravis
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9
Q

Beclomethasone

A

Corticosteroid

  • asthma
  • oral ulceration
  • resistant eczema
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10
Q

Rosiglitazone

A

Diabetes drug- Banned due to increased risk of CVD

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11
Q

Ondansetron

A

Antiemetic

  • emetogenic Chemo/radio
  • post op nausea and vom
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12
Q

Tamulosin

A

Alpha adrenergic blocker

-BPH

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13
Q

Salmeterol

A

Beta agonist

  • COPD
  • asthma
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14
Q

Fludrocortisone

A

Steroid

  • adrenocorticol insufficiency
  • neuropathic postural HTN
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15
Q

Quinine

A

Antimalarial

  • malaria
  • nocturnal leg cramps
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16
Q

Carbimazole

A

Thionamide

-hyperthyroidism

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17
Q

Tropicamide

A

Anticholingeric

-dilating pupil for eye exam

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18
Q

Ranitidine

A

H2 receptor agonist

  • gastric ulceration
  • dyspepsia
  • GORD
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19
Q

Loperamide

A
  • diarrhoea

- faecal incontinence

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20
Q

Oxygen

A
  • COPD
  • ILD
  • pHTN
  • CHF
  • sleep apnoea
  • sepsis
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21
Q

Chloroquine

A

Antimalarial

  • RA
  • malaria
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22
Q

Cetirizine

A

Antihistamine

  • hay fever
  • urticaria
  • dermatitis
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23
Q

Domperidone

A

Antiemetic

-nausea and vom

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24
Q

Furosemide

A

Loop diuretic

  • oedema
  • resistant HTN
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25
Q

Lansoprazole

A

PPI

  • GORD
  • oesphagitis
  • dyspepsia
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26
Q

Senna

A

Laxative

-constipation

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27
Q

Spironolactone

A

K sparing diuretic

  • oedema
  • cirrhosis ascities
  • oedema in CHF
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28
Q

Metoclopromide

A

Pro kinetic/ antiemetic

-nausea and vom

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29
Q

Metformin

A

Biguanides

  • T2DM
  • PCOS
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30
Q

Cisplatin

A

Antineoplastic

-testicular/ lung/ cervical/ back/ head and neck/ ovarian cancer

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31
Q

Hydrocortisone

A

Glucocorticoid

  • thyroid storm
  • adrenocorticol deficiency
  • angioedema
  • eczema
  • asthma
  • oral/ perioral lesions
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32
Q

Cyclosporin

A

Immunosuppressant

  • Severe: UC, RA, dermatitis, psoriasis
  • organ transplant
  • nephrotic syndrome
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33
Q

N-acetylcystine

A

Mucolytic agent

  • CF
  • paracetamol OD
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34
Q

Salbutamol

A

B-adrenergic agonist

-asthma

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35
Q

Levothyroxine

A

Hormone

-hypothyroidism

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36
Q

Simvastatin

A

Statin

  • hyperchloestralaemia
  • hyperlipidaemia
  • CVD
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37
Q

Glycerol Trinitrate

A

Vasodilator

  • angina
  • anal fissue
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38
Q

Dalteparin

A

Anticoagulant

  • CAD
  • DVT prophylaxis
  • DVT/ PE treatment
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39
Q

Aspirin

A

Antiplatelet

  • CVD
  • angina
  • TIA
  • ischaemic stroke
  • AF
  • Pain
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40
Q

Rivaroxiban

A

Anticoagulant

  • DVT
  • PE
  • CVA/ CVD
  • ACS
  • PAD
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41
Q

Losartan

A

ARB

  • diabetic nephropathy
  • 2nd like: CHF
  • HTN
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42
Q

Nicorandil

A

Vasodilator

-stable angina

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43
Q

Dobutamine

A

B1 agonist

  • septic shock
  • cardiogenic shock
  • ventilation
  • cardiac surgery
  • cardiac stress testing
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44
Q

Diltiazem

A

CCB

  • angina
  • chronic anal fissure
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45
Q

Ramipril

A

ACE inhibitor

  • HTN
  • CHF
  • CVD
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46
Q

Digoxin

A

Cardiac glycoside

  • AF
  • atrial flutter
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47
Q

Amlodipine

A

CCB

  • angina
  • HTN
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48
Q

Verapamil

A
  • supraventricular arrhythmia
  • angina
  • HTN
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49
Q

Isosorbide mononitrate

A

Vasodilator

  • angina
  • CHF
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50
Q

Adrenaline

A

-CPR: 1mg 3-5mins
-Anaphylaxis:
<5 years= 150micrograms
6-11= 300micrograms
>12= 500micrograms

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51
Q

Bisoprolol

A

Beta blocker

  • HTN
  • Angina
  • CHF
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52
Q

Atenolol

A

Beta blocker

  • HTN
  • angina
  • arrhythmia
  • migraine
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53
Q

Amiodarone

A

Class III anti arrhythmtic

-arrhythmias

54
Q

Clopidogrel

A

Antiplatelet

  • TIA
  • ischaemic stroke
  • MI
  • AF
55
Q

Warfarin

A

Anticoagulant

  • AF
  • prosthetic heart valve
  • rheumatic heart disease
  • PE
  • TIA
56
Q

Alendronate

A

Bisphosphonate

-osteoporosis

57
Q

Adenosine

A

Organic compound

-paroxysmal supraventricular tachycardia

58
Q

Insulin

A
  • diabetes I and II

- diabetic ketoacidosis

59
Q

Glucagon

A

Antihypoglycaemic

  • hypoglycaemia
  • beta blocker poisoning
60
Q

Streptokinase

A

Fibrinolytic

  • MI
  • DVT
  • PE
  • PAD
61
Q

Lactulose

A

Laxative

-constipation

62
Q

Folic acid

A
  • folate deficient anaemia

- prevention of neural tube defects in pregnancy

63
Q

Gliclazide

A

Sulphonylurea

-T2DM

64
Q

Hydroxycobalamin

A

Vitamin B12

  • B12 deficiency anaemia
  • pernicious anaemia
65
Q

Ferrous sulphate

A

Iron

-iron deficiency anaemia

66
Q

Ad-Cal-D3

A

Vitamin D and calcium

  • vit d / Ca deficiency
  • osteoporosis
  • rickets
67
Q

Ipratropium

A

Muscarinic agonist/ SABA

  • COPD
  • asthma
68
Q

Carbamazapine

A

Anticonvulsant

  • generalised seizures
  • trigeminal neuralgia
  • diabetic neuropathy
69
Q

Citalopram

A

SSRI

  • depression
  • panic disorder
70
Q

Amitriptyline

A

TCA

  • neuropathic pain
  • migraine
71
Q

Diamorphine

A

Analgesic

  • pain
  • pulmonary oedema
  • MI
72
Q

Diclofenac

A

NSAID

-pain (gout, RA, post-op)

73
Q

Celecoxib

A

Cox II inhibitor

-pain (osteoarthritis, RA, AS)

74
Q

Diazepam

A

Benzodiazepam

  • muscle spasm
  • tetanus
  • anxiety
  • insomnia
  • sedation for surgery
  • convulsions
75
Q

Ibuprofen

A

NSAID

  • MSK lain/ inflammation
  • pyrexia with discomfort
76
Q

Gabapentin

A

Anticonvulsant

  • focal seizures
  • neuropathic pain
  • menopause
  • spascity in MS
77
Q

Fluoxetine

A

SSRI

  • depression
  • bulimia
  • OCD
  • menopause
78
Q

Lamotrigine

A

Anticonvulsant

  • focal seizures
  • general seizures
  • bipolar
79
Q

Lignocaine

A

Local anaesthetic

80
Q

Lithium

A

Mood stabiliser

  • mania
  • bipolar
  • recurrent depression
  • self harm
81
Q

Paracetamol

A

Analgesic

  • pain
  • pyrexia
82
Q

Nitrous oxide

A

Analgesic

-pain

83
Q

Sertraline

A

SSRI

  • depression
  • anxiety disorder
84
Q

Tramadol

A

Opioid analgesic

-pain

85
Q

Isofluorane

A

General anaesthetic

86
Q

Haloperidol

A

Antipsychotic

  • nausea and vomit
  • schizophrenia
  • delirium
  • BP in mania
87
Q

Flumazenil

A

GABA receptor agonist

-reverses affects of benzodiazepines

88
Q

Mirtazipine

A

Tetracyclic antidepressant

-major depression

89
Q

Sildenafil

A

Phosphesterase-5-inhibitor
(Viagra)
-erectile dysfunction

90
Q

Naloxone

A

Opioid antagonist

-opioid overdose

91
Q

Suxamethonium

A

Neuromuscular blocker

-short term paralysis of general anaesthesia

92
Q

Zopiclone

A

Cyclopyrrolone

-insomnia

93
Q

Sumatriptan

A

Serotonin receptor agonist

  • migraine
  • cluster headache
94
Q

Propofol

A

General anaesthetic

-induction / maintenance of general anaesthesia

95
Q

Pregabalin

A

Anticonvulsant

  • neuropathic pain
  • focal seizures
  • GAD
96
Q

Phenytoin

A

AED

  • TC seizures
  • status epilepticus
  • focal seizures
97
Q

Ephedrine

A

Amphetamine

  • reversible HTN from epidural
  • reversible airway obstruction
  • neuropathic oedema
  • nasal congestion
98
Q

Chlorpromazine

A

Antipsychotic

  • schizophrenia
  • mania
  • agitation
99
Q

Sodium valproate

A

Anti epileptic

  • epilepsy
  • migraine prophylaxis
100
Q

Nefopam

A

Analgesic

-pain (moderate)

101
Q

Methadone

A

Opiate

  • pain
  • opioid dependence
102
Q

Atracurium

A

Neuromuscular blocker

-neuromuscular blockade for surgery / intensive care

103
Q

Hyoscine

A

Antispasmodic

  • motion sickness
  • hyper saliva
  • bowel colic
104
Q

Donepezil

A

Cholinesterase inhibitor

-Alzheimer’s

105
Q

Thiamine

A

Vitamin B1

106
Q

Aciclovir

A

Anti viral

  • herpes zoster
  • herpes simplex
107
Q

Fluconazole

A

Antifungal

-candidiasis

108
Q

Nystaitin

A

Anti fungal

-oral candidiasis

109
Q

Levonorgestrel

A

Progestin hormone

  • contraception (IUD, oral)
  • menorrhagia
  • emergency contraception pill
110
Q

Oxytocin

A

Peptide hormone

  • labour induction
  • C section
  • prevention of postpartum haemorrhage
111
Q

Oestradiol

A

Oestrogen

  • dysfunctional uterine bleeding
  • contraception
  • endometriosis
  • endometrium / renal cell / breast cancer
112
Q

Medroxyprogesterone

A

Progestin hormone

  • dysfunctional uterine bleeding
  • secondary amenorrhoea
  • contraception
  • endometrial / breast cancer
113
Q

Goserlin

A

LHRH agonist

  • prostate cancer
  • breast cancer
114
Q

Ethinylestradiol

A

Oestrogen

  • oestrogen deficiency
  • female hypogondism
  • menstrual disorders
115
Q

Finasteride

A

5 alpha-reductase inhibitor

  • BPH
  • androgenetic alopecia
116
Q

Rifampicin

A

ABx

  • endocarditis
  • TB
  • H. Influenzae type b
117
Q

Nitrofurantoin

A

ABx

-UTI

118
Q

Ciprofloxacin

A

Broad spectrum ABx

  • eye infection
  • diabetic foot/ ulcer
  • fistulating crohns
  • RTI
  • UTI
  • diarrhoea travelling prophylaxis
  • gonorrhoea
119
Q

Vancomycin

A

Narrow spectrum

  • C. Difficile infection
  • diabetic foot/ ulcer
  • bone and joint infections
  • CAP
  • HAP
  • bacterial meningitis
120
Q

Erythromycin

A

Broad spectrum ABx

  • penicillin allergy
  • cellulitis
  • foot infection
  • CAP
  • syphilis
  • chronic prostatitis
  • acne
121
Q

Tetracycline

A

Broad spectrum ABx

  • rosacea
  • acne
  • H. Pylori
  • non-gonococcal urethritis
122
Q

Doxycycline

A

Broad spectrum ABx tetracycline

  • chlamydia
  • UTI
  • sinusitis
  • HAP
  • acne
  • rosacea
  • syphilis
  • Lyme disease
  • malaria
123
Q

Co-trimoxazole

A

ABx

  • HAP
  • leg ulcer
  • diabetic foot
  • COPD exacerbation
124
Q

Metronidazole

A

ABx

  • diabetic foot
  • cellulitis
  • H. Pylori
  • BV
  • oral infection
  • liver abscess
125
Q

Do-amoxiclav

A

Broad spectrum ABx

  • RTI
  • UTI
  • bone and joint infection
  • abdo infection
  • animal bites
  • CAP/ HAP
126
Q

Amoxicillin

A

Penicillin ABx

  • pneumonia
  • bronchiectasis
  • acute COPD
  • Lyme disease
  • anthrax
  • H. Pylori
  • UTI
127
Q

Flucloxacillin

A

Narrow spectrum ABx

  • cellulitis
  • diabetic foot
  • leg ulcer
  • CF lung infections
128
Q

Trimethoprim

A

ABx penicillin

  • RTI
  • UTI
  • acne
  • GU infections
129
Q

Cefuroxime

A

ABx cephalosporin

  • cellulitis
  • acute diverticulitis
  • Lyme disease
  • fracture prophylaxis
  • UTI
130
Q

Chloramphenicol

A

ABx

  • eye infection
  • bacterial infection in otitis externa
  • typhoid fever
131
Q

Gentamicin

A

Broad spectrum ABx

  • eye infection
  • diabetic foot
  • otitis externa
  • gram positive endocarditis