Drugs Flashcards
disease-modifying antirheumatic agents
(DMARD) slow/halt progression of rheumatic disease, inhibit immune response
DMARD side effects
Nausea, headache, joint pain and swelling, toxicity, GI distress, sore throat, fever, liver dysfunction, hair loss, potential for sepsis, retinal damage
Rheumatrex (methotrexate)
DMARD
Arava (leflunomide)
DMARD
Aralen (chloroquine) and Plaquenil (hydroxycholorquine)
DMARD - antimalarial
Ridaura (auranofin) and Solganal (aurothioglucose)
DMARD - gold compounds
Humira (adalimumbab) and Enbrel (entanercept)
DMARD - tumor necrosis factor inhibitors
Glucocorticoid agents
Hormonal, anti inflammatory, and metabolic effects; endocrine dysfunction, rheumatic, respiratory, other
Glucocorticoid agent side effects
Muscle atrophy!!!, GI distress, glaucoma, adrenocorticol supression, drug-induced Cushing’s syndrome, weakening with breakdown of supporting tissues! (bone, ligament, tendon, skin), mood changes, hypertension
Dermacort (hydrocortisone or cortisol)
Glucocorticoid/corticosteroid
Cordrol (prednisone), Pediapred (prednisolone), Medrol (methylprednisolone)
Glucocorticoid/corticosteroid
Decadrol (dexamethasone), Nasonex (mometasone)
Glucocorticoid/corticosteroid
Opioid agents (narcotics)
Provides analgesia, stimulates opioid receptors in CNS to prevent pain impulse from reaching their destination
opioid side effects
Mood swings, sedation, confusion, vertigo, dulled cognitive function, orthostatic hypotension, constipation, incoordination, physical dependence, tolerance
Roxanol (morphine), OxyContin (oxycodone), Paveral (codeine)
Opioids
