Drugs

Question 1

Edrophonium

Answer 1

Reversible acetylcholinesterase inhibitor - competitive inhibitor - used in tension test

Question 2

Rocuronium, atracurinium, verocuronium, pancuronium, suxamethonium

Answer 2

Anaesthetic -> antagonist at neuromuscular junctions, competitively inhibits the nicotinic acetylcholine choline receptor blocking the binding of acetylcholine choline

Question 3

Neostigmine, pyrisodtigmine, physostigmine, rivastigmine, donepezil, galantimine

Answer 3

Inhibit cholinesterases so prevent the breakdown of acetylcholine choline at neuromuscular junctions

Question 4

Dantrolene

Answer 4

Inhibits the release of calcium ions from the sarcoplasmic reticulum - so is a muscle relaxant

Question 5

bethanechol, pilocarpine, physostigmine neostigmine, ecothipoate

Answer 5

Muscarinic receptor agonists

Question 6

Atropine, hyoscine, scopolamine, benzotropine

Answer 6

Muscarinic receptor antagonists

Question 7

Isoprenaline

Answer 7

Non selective beta adrenoreceptor agonist

Relax muscles of the airways and heart

Question 8

Warfarin

Answer 8

Vitamin K acting anticoagulant

Question 9

Clonidine

Answer 9

Alpha 1 and 2 adrenergic agonist

hypotension drug -> widens blood vessels

Question 10

Dobutamine

Answer 10

Beta one receptor agonist

Used in treatment of cardiogenic shock or severe heart failure as increases contraction to and cardiac output

Question 11

Salbutamol

Answer 11

Short acting beta2-adrenergic receptor agonist

Used in treatment of asthma and COPD

Question 12

Prazosin

Answer 12

Alpha 1 inverse agonist (does complete opposite of regular ligand)

Treats high blood pressure and benign prostatic hyperplasia

Question 13

Propranolol, atenolol

Answer 13

Beta blocker

Used to treat high plod pressure, irregular heart rate etc.

Question 14

Yohimbine

Answer 14

Alpha-2 adrenergic antagonist

Erectile dysfunction

Question 15

Butoxamine

Answer 15

B2 selective beta blocker

Question 16

Yellow card scheme

Answer 16

System for recording adverse incidents with medicines and medical devices in the UK

Monitored by the medicines and healthcare products regulatory agency

Doctors and general public report adverse drug reactions and are collated to look for patterns