Drugs Flashcards

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1
Q

What neurotransmitter is Serotonin

A

Monoamine

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2
Q

What neurotransmitter is Norepinephrine

A

Monoamine

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3
Q

What neurotransmitter is Dopamine

A

Monoamine

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4
Q

What neurotransmitter is Acetylcholine

A

Cholinergic

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5
Q

What neurotransmitter is GABA

A

Amino Acid

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6
Q

What does GABA do?

A

It is an inhibitory Amino acid so it calms you down and relaxes

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7
Q

What does excess dopamine cause?

A

Psychotic symptoms

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8
Q

What does low serotonin cause?

A

Depression

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9
Q

Depakote therapeutic level

A

50-100

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10
Q

What is Depakote for?

A

Anticonvulsant as well as mood stabilizer for manic episodes

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11
Q

What is Tegretol used for?

A

Anticonvulsant that treats seizures and is a mood stabilizer for manic episodes

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12
Q

Tegretol therapeutic level

A

3-12

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13
Q

Lithium therapeutic level

A

0.6-1.2

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14
Q

What is Lithium used for?

A

Mood stabilizer for manic depressive illness in bipolar individuals

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15
Q

What is Lamictal used for?

A

Depressive symptoms

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16
Q

What are SSRI’s used for?

A

Anxiety and Depression

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17
Q

What is Klonopin (Clonazepam)

A

Benzo

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18
Q

What is Ativan (Lorazepam)

A

Benzo

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19
Q

What is Xanax (Alprazolam)

A

Benzo

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20
Q

What is Valium (Diazepam)

A

Benzo

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21
Q

What is something to keep in mind with patient education about Benzos

A

Dose needs to be tampered down, not abruptly stopped because it can cause a seizure if abruptly stopped or recurrence of symptoms
Do not take with alcohol
Causes drowsiness and dizziness, confusion, headache, blurred vision, dependence

22
Q

What are the side effects of 1st generation psychotropics “neuroleptic”?

A

EPS: Dyskinesias (movement disorders) and Dystonias (muscle tension disorder)

23
Q

What is Tardative Dyskinesia?

A

Side effect of 1st gen: Blinking, Lip smacking, sucking or chewing, rolling or protruding tongue, grimaces
Can be permanent so stop drugs immediately

24
Q

What is Thorazine (Chlorpromazine)

A

Type 1 psychotropics

25
Q

What is Haldol (Haloperidol)

A

Type 1 psychotropics

26
Q

What is Trilafon (Perphanazine )

A
Type 1 psychotropic
Side effects: 
Loss of coordination 
Excessive thirst 
Frequent urination 
Blackouts 
Seizures 
Slurred speech 
Fast, slow, irregular, or pounding heartbeat 
Muscle spasms (hypo vs hyper -reflexia)
(Good for manic)
27
Q

What is Prolixin (Fluphenazine)

A

Type 1 Psychotropic

28
Q

What is akinesia

A

A common side effect of type 1 psychotropic, is is motor inertia

29
Q

What is dystonia

A

Peculiar involuntary posture

30
Q

What is parkinsonism

A

Shuffling gait

31
Q

What is Clozaril (Clozapine)

A

Type 2 psychotropic (Can cause agranulocytosis)

32
Q

Type 2 psychotropic side effect

A

Metabolic syndrome: truncal obesity, diabetes, hyperlipidemia, hypertension

33
Q

What is Prozac

A

Serotonin SSRI

34
Q

What is Celexa

A

Serotonin SSRI

35
Q

What is Zoloft

A

Serotonin SSRI

36
Q

What is Paxil

A

Serotonin SSRI

37
Q

What is Lexapro

A

Serotonin SSRI

38
Q

What is Effexor

A

Norepinephrine SNRI

39
Q

What is Cymbalta

A

Norepinephrine SNRI

40
Q

What is Pristiq

A

Norepinephrine SNRI

41
Q

What is Wellbutrin

A

Dopamine DNRI

42
Q

What to keep in mind when someone goes on antidepressants?

A

Patient can feel jittery, headache, nausea, sleeplessness, reduced sex drive, suicidal ideations, drowsy

43
Q

How often do you check therapeutic serum levels of someone on antidepressants?

A

every 3 months

44
Q

What is an issue with tricyclics?

A

They can cause cardiotoxicity

45
Q

What to avoid with monoamines

A

TYRAMINE

46
Q

Foods with Tyramine

A

Cheese, Wine, Soy sauce, Pickles, fermented meats, red wine, miso soup, ripe bananas

47
Q

What happens if MAOIs mix with Tyramine?

A

Hypertensive crisis

48
Q

What MAOI can you have with Tyramine?

A

Selegiline “EMSAM”, Low dose 3 mg

49
Q

When would you give a psychotropic drug?

A

Patients with schizophrenia

50
Q
Amitriptyline (Elavil)
Clomipramine (Anafranil)
Desipramine (Norpramin)
Doxepin (Sinequan)
Imipramine (Tofranil)
Nortriptyline (Pamelor)
A

Tricyclics