Drugs Flashcards

1
Q

Oxygen indications

A
  • Chest pain or SOB for any reason
  • 10-15 L/min by non-rebreather mask
  • Don’t mess with NC, not enough at 6 L/min max
  • Positive pressure in cardiopulmonary arrest
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2
Q

Oxygen indication for positive pressure in cardiopulmonary arrest

A
  • Bag-valve-mask with an oropharyngeal airway (BVM with an OPA)
  • Laryngeal mask airway (LMA)
  • Endotrachial tube
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3
Q

Epinephrine indications

A
  • V-fib
  • pulseless V-tach
  • PEA
  • asystole
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4
Q

Epinephrine MOA

A

Increases:

  • systemic vascular resistance
  • arterial pressure
  • heart rate
  • contractility
  • myocardial oxygen demand
  • automaticity
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5
Q

Epinephrine dose

A

1 mg Q 3-5 mins (IV or IO)

  • No max dose
  • 10 ml of 1:10,000 soln = 1 mg
  • 2.5 X IV dose down ET tube
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6
Q

Amiodarone indications

A
  • V-fib, pulseless v-tach
  • wide complex v-tach
  • SVT due to WPW
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7
Q

Amiodarone MOA

A
  • suppresses ectopy
  • increases atrial, AV and ventricular refractory periods
  • antianginal effect
  • slows sinus rate
  • prolongs QRS and QT intervals
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8
Q

Amiodarone dose

A
  • 300 mg, may rebolus 150 mg in v-fib/pulseless v-tach, PSVT
  • 150 mg over 10 min, may bolus once in wide complex v-tach
  • drip rate 0.2-2 mg/min
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9
Q

Atropine indications

A

bradycardia

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10
Q

Atropine MOA

A
  • parasympatholytic
  • accelerates rate of SA discharge
  • improves AV conduction
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11
Q

Atropine dose

A
  • 0.5 mg IV q 3-5 min prn

- MAX dose 3 mg

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12
Q

Adenosine indications

A
  • SVT

- diagnostic tool in stable VT

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13
Q

Adenosine MOA

A
  • slows AV conduction
  • interrupts AV nodal re-entry pathway
  • may worsen SVT due to WPW
  • half-life is less than 10 seconds
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14
Q

Adenosine dose

A
  • 6 mg IV push followed by 20 cc saline flush
  • may repeat at 12 mg IV in 1-2 minutes
  • may repeat 12 mg dose once more
  • sinus pause if effective
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15
Q

Diltiazem (Cardizem) indications

A
  • SVT

* *DO NOT use in WPW, AV block, with IV beta-blockers

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16
Q

Diltiazem (Cardizem) MOA

A
  • calcium channel blocker
  • prolongs AV nodal conduction
  • decreases systemic vascular resistance
17
Q

Magnesium sulfate indications

A
  • Torsades de pointes

- post-MI

18
Q

Magnesium sulfate MOA

A
  • NA and K channel blocker
  • blocks neuromuscular transmission
  • magic
19
Q

Magnesium sulfate dose

A
  • 1-2 gm IV over 5-50 min in torsades

- 0.5-1.0 gm/hr infusion in post-MI

20
Q

Nitroglycerin indications

A
  • angina
  • MI

*if BP and HR allow

21
Q

Nitroglycerin MOA

A
  • dilates coronary arteries – and others

- decreases ventricular work/volume/venous return

22
Q

Nitroglycerin dose

A
  • 0.4 mg SL q 5 mins X 3, tabs or spray
  • may apply 1 inch nitropaste
  • IV rate 10-20 mcg/min, may increase by 5

**watch for hypotension with all

23
Q

Dilaudid indications

A
  • morphine is NO MORE!
  • acute MI
  • acute pulmonary edema
24
Q

Dilaudid MOA

A
  • vasodilator

- opioid analgesic

25
Q

Dilaudid dose

A
  • monitor hemodynamic effect

- dilaudid (hydromorphone) 1-4 mg IV titrated to desired analgesic

26
Q

Dopamine/Dobutamine indications

A
  • bradycardia
  • hypotension/cardiogenic shock
  • CHF – with other drugs
27
Q

Dopamine/Dobutamine MOA

A
  • precursor of epi
  • alpha- and beta-adrenergic agonist
  • arterial and venous constriction
  • dopamine increases myocardial oxygen demand, dobutamine does not
28
Q

Dopamine/Dobutamine Dose

A
  • 5-10 mcg/kg/min

- adjust to desired BP, urine output and clinical response