Drugs Flashcards

Week 2

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1
Q

Enoxaparin (Lovenox)

Class

A

Anticoagulant-low molecular weight heparin/ heparin derivative.

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2
Q

Enoxaparin (Lovenox)

Mechanism of Action

A

Deactivates thrombin. Also prevents the conversion of fibrinogen to fibrin.

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3
Q

Enoxaparin (Lovenox)

Indications

A

Used to inhibit clot formation in ACS including STEMI, NSTEMI, and unstable angina. It is also used to prevent pulmonary embolism and DVT in patients predisposed to such problems.

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4
Q

Enoxaparin (Lovenox)

Contraindications

A

Known hypersensitivity to the medication, pork products, or heparin.

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5
Q

Enoxaparin (Lovenox)
Adverse Reactions,
CNS System

A

CNS side effects include confusion and dizziness.

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6
Q

Enoxaparin (Lovenox)
Dosage,
Adult, STEMI

A

Single IV bolus of 30 mg plus 1 mg/kg SQ dose followed by 1 mg/kg SQ every 12 hours (maximum 100 mg)

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7
Q

Enoxaparin (Lovenox)
Dosage,
Adult, NSTEMI, Unstable Angina

A

1 mg/kg SQ every 12 hours in conjunction with oral aspirin therapy (100-325 mg daily)

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8
Q

Enoxaparin (Lovenox)
Dosage,
Pediatric

A

1 mg/kg SQ

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9
Q

Enoxaparin (Lovenox)

Special Considerations

A

Do not use in patients with active major bleeding or thrombocytopenia. Use with caution in the elderly or any patient with increased risk of bleeding.

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10
Q

Enoxaparin (Lovenox)

Onset

A

Onset 3-5 hours

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11
Q

Enoxaparin (Lovenox)

Peak Effect

A

Peak effects: 3-5 hours

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12
Q

Enoxaparin (Lovenox)

Duration

A

Duration: Varies

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13
Q

Enoxaparin (Lovenox)

Drug Interactions

A

Interacts with NSAIDs, warfarin, and anti-platelet agents.

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14
Q

Enoxaparin (Lovenox)
Adverse Reactions,
Cardiovascular

A

edema, chest pain, and irregular heartbeat.

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15
Q

Enoxaparin (Lovenox)
Adverse Reactions,
Injection Site

A

Irritation, pain, redness or bruising

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16
Q

Enoxaparin (Lovenox)

Other Adverse Reactions

A

angioedema, bleeding, hives, and, rash

17
Q

Captopril (Capoten)

Class

A

Angiotensin-converting enzyme (ACE) inhibitor

18
Q

Captopril (Capoten)

Mechanism of action

A

Blocks the enzyme responsible for the production of angiotensin II, which causes an interruption of the renin-angiotensin-aldosterone (RAA) system thereby decreasing blood pressure.

19
Q

Captopril (Capoten)

Indication

A

Hypertension, Congestive Heart Failure

20
Q

Captopril (Capoten)

Contraindications

A
Previous episode(s) of angioedema related to prior ACE
inhibitor treatment, known hypersensitivity;
21
Q

Captopril (Capoten)

Adverse Reactions

A

Angioedema, chest pain, cough, dizziness, dyspnea fatigue, headache, hypotension, palpitations.

22
Q

Captopril (Capoten)

Drug Interactions

A

Use with caution in patients on other anti-hypertensives.

23
Q

Captopril (Capoten)
Dosage and Admin,
Adult

A

12.5-25 mg mg sublingually every 6 hours

24
Q

Captopril (Capoten)
Dosage and Admin,
Pediatric

A

Not recommended in the prehospital setting

25
Q

Captopril (Capoten)
Duration of Action,
Onset

A

15-30 Minutes

26
Q

Captopril (Capoten)
Duration of Action,
Duration

A

4-6 Hours

27
Q

Ibuprofen
(Motrin, Advil)
Class

A

NSAID

28
Q

Ibuprofen
(Motrin, Advil)
Mechanism of Action

A

Anti-inflammatory, prostaglandin inhibitor

29
Q

Ibuprofen
(Motrin, Advil)
Indications

A

Mild to moderate pain, fever

30
Q

Ibuprofen
(Motrin, Advil)
Contraindications

A

hypersensivity, pts taking other NSAIDs

31
Q

Ibuprofen
(Motrin, Advil)
Side Effects

A

heartburn, nausea, vomiting, wheezing

32
Q

Ibuprofen
(Motrin, Advil)
Dosage and Administration
Adult

A

200-800 mg/dose PO

33
Q

Ibuprofen
(Motrin, Advil)
Dosage and Administration
Pediatric

A

5-10 mg/kg/dose PO every 4-6 hours