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ESA 2- Membranes and Receptors > Drugs > Flashcards

Drugs Flashcards

1
Q

Give an example of a nicotinic cholinoceptor antagonist?

A

Tubocararine

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2
Q

What is the action of tubocurarine?

A

Muscle paralysis during anasthesia

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3
Q

Give 4 examples of muscarinic cholinoceptor antagonists

A

HyoscineIpratropium bromideHomatropine Tropicamide

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4
Q

What is hyoscine used for?

A

Anaesthetic premedication

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5
Q

What is ipratropium bromide used for?

A

Treat bronchoconstriction in asthmatics

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6
Q

What is homatropine and tropicamide used for?

A

Pupillary dilation and paralysis

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7
Q

Give an example of a muscarinic cholinoreceptor agonist?

A

Pilocarpine

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8
Q

What is pilocarpine used for?

A

Treatment of glaucoma Increased GI motility after surgerySuppression of atrial tachycardia Stimulates bladder emptying

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9
Q

Give 5 examples of cholinesterase inhibitors

A

Edrophonium Physostigimine Dyflos TacrineDonepezil

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10
Q

What is edrophonium, physostigimine, and dyflos used for?

A

Treatment of glaucomaMyasthenia gravis

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11
Q

What is tacrine and donepezil used for?

A

Treatment of Alzheimer’s disease

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12
Q

Give an example of a selective ß1 agonist

A

Dobutamine

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13
Q

What does dobutamine do?

A

NAME?

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14
Q

Give an example of a selective ß2 agonist

A

Salbutamol

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15
Q

What does salbutamol do?

A

Bronchodilation

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16
Q

Give two examples of a selective α1 agonist?

A

Phenylephrine Adrenaline

17
Q

What is phenylephrine used for?

A

Nasal decongestants

18
Q

What is adrenaline used for?

A

Local vasoconstriction to retard the dissipation of anaesthetic

19
Q

Give an example of a selective α2 agonist

A

Clonidine

20
Q

What is clonidine used for?

A

Anti-hypertension

21
Q

What does clonidine do?

A

Acts on presynaptic receptors to reduce NA release

22
Q

Give an example of a α-antagonist

A

Phentolamine

23
Q

What does phentolamine do?

A

Peripheral vasodilation

24
Q

What is phentolamine used for?

A

To treat peripheral vascular disease

25
Q

Why is phentolamine not used to treat hypertension?

A

It can cause postural hypotension

26
Q

Give an example of a selective α1 antagonist

A

Prazosin

27
Q

What is prazosin used for?

A

Treat hypertension

28
Q

Give an example of a ß-antagonist (blocker)

A

Propanolol

29
Q

What is propanolol used for?

A

Treat hypertension, MI, angina

30
Q

What are the unwanted side effects of propanolol?

A

Bronchoconstriction

ESA 2- Membranes and Receptors (13 decks)

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