Drugs Flashcards
Give an example of a nicotinic cholinoceptor antagonist?
Tubocararine
What is the action of tubocurarine?
Muscle paralysis during anasthesia
Give 4 examples of muscarinic cholinoceptor antagonists
HyoscineIpratropium bromideHomatropine Tropicamide
What is hyoscine used for?
Anaesthetic premedication
What is ipratropium bromide used for?
Treat bronchoconstriction in asthmatics
What is homatropine and tropicamide used for?
Pupillary dilation and paralysis
Give an example of a muscarinic cholinoreceptor agonist?
Pilocarpine
What is pilocarpine used for?
Treatment of glaucoma Increased GI motility after surgerySuppression of atrial tachycardia Stimulates bladder emptying
Give 5 examples of cholinesterase inhibitors
Edrophonium Physostigimine Dyflos TacrineDonepezil
What is edrophonium, physostigimine, and dyflos used for?
Treatment of glaucomaMyasthenia gravis
What is tacrine and donepezil used for?
Treatment of Alzheimer’s disease
Give an example of a selective ß1 agonist
Dobutamine
What does dobutamine do?
NAME?
Give an example of a selective ß2 agonist
Salbutamol
What does salbutamol do?
Bronchodilation
Give two examples of a selective α1 agonist?
Phenylephrine Adrenaline
What is phenylephrine used for?
Nasal decongestants
What is adrenaline used for?
Local vasoconstriction to retard the dissipation of anaesthetic
Give an example of a selective α2 agonist
Clonidine
What is clonidine used for?
Anti-hypertension
What does clonidine do?
Acts on presynaptic receptors to reduce NA release
Give an example of a α-antagonist
Phentolamine
What does phentolamine do?
Peripheral vasodilation
What is phentolamine used for?
To treat peripheral vascular disease
Why is phentolamine not used to treat hypertension?
It can cause postural hypotension
Give an example of a selective α1 antagonist
Prazosin
What is prazosin used for?
Treat hypertension
Give an example of a ß-antagonist (blocker)
Propanolol
What is propanolol used for?
Treat hypertension, MI, angina
What are the unwanted side effects of propanolol?
Bronchoconstriction