Drugs Flashcards

1
Q

What medication should always be avoided in patients with mononucleosis

A

Amoxicillin

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2
Q

A patient has been diagnosed with acute rhinosinusitis. Symptoms began 3 days ago. Based on the most likely etiology, how should this patient be managed?

A

Decongestant and analgesic

conservative measures should be used for 7-10 days prior to antibiotic use

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3
Q

Another name for fexofenadine

A

Allegra

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4
Q

What is the most effective single maintenance medication for allergic rhinitis?

A

Intranasal glucocorticoids

Intranasal glucocorticoids are effective in relieving nasal congestion, discharge, itching, and sneezing

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5
Q

First line therapy for otitis media

A

Amoxicillin

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6
Q

Antibiotics treatment for patient with ARBS that are beta-lactam allergy

A

Doxycycline 100mg

Respiratory Fluoroquinolones (Only use with DRSP risk)

Allergy to antimicrobials with beta-lactam ring, such as penicillins and cephalosporins

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7
Q

Antimicrobial tx for ABRS in adults

A

1st line therapy: Amoxicillin-Clavulante 500 mg

2nd line: Amoxicillin-Clavulanate 2000mg

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8
Q

What is DRSP

A

Drug resistant S. Pneumonia

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9
Q

First line therapy for Allergic Rhinitis

A

Intranasal corticosteroids

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10
Q

Example of intranasal corticosteroids

A

Fluticasone propionate (Flonase)

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11
Q

Antibiotics with beta-lactam ring

A

Penicillins

Cephalosporins

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12
Q

Example of CYP450 3A4 substrates:

A

Sildenafil (Viagra)

Astorvastatin; Simvastatin

Venlafaxine (Effor)

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13
Q

Example of inhibitor

A

Macrolids

Erythro/Clarithromycin

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14
Q

Example of inducers

A

St.John’s wort

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15
Q

Medication that utilizes a specific enzymatic pathway

A

Substrate….CYP450 3A4

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16
Q

Medication that blocks a specific enzymatic pathway, keep substrate from exisiting

A

inhibitor

risk of substrate-induced toxicity

17
Q

Medication that pushes substrate out the exit pathway

A

inducers

lead to reduction in substrate level..possible treatment failure

18
Q

Medication of more concern for inducers

A

antiretrovirals

oral contraceptives

cyclosporine