Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Neuro Pt 2 > Drugs > Flashcards

Drugs Flashcards

1
Q

Lidocaine

A

Amide local anesthetic (Na channel blocker)

Block of VSSC acts to diminish excessive channel activity and the pain associated with neuropathic damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Bupivacaine

A

Amide local anesthetic (Na channel blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Morphine

A

Opioid (μ) receptor agonist
Schedule II
Relieves severe pain (post-operatively and in acute trauma (IV/IM)
Oral sustained release form can be used for chronic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hydrocodone

A

Opioid (μ) receptor agonist
Antitussive
Weak analgesic
Similar to codeine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Oxycodone

A

Opioid (μ) receptor agonist
Equipotent with morphine
LOTS of abuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Codeine

A 
Opioid (μ) receptor agonist
Schedule II or III
Most commonly used opioid analgesic
CYP2D6 metabolism and 10% of caucasians are deficient, so not a good analgesic for those pts
ANTITUSSIVE
Less potent than morphine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tramadol

A

Opioid (μ) receptor agonist

Also blocks monoamine uptake to potentiate descending pain pathway (like antidepressants)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fentanyl

A 
Opioid (μ) receptor agonist
Schedule II
100x more potent than morphine
Used for post-operative and peri-operative pain management
Short duration of action
Can have severe respiratory depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Combos of opioid agonists with NSAIDs

A

Codeine-acetaminophen (Tylenol #3), Codeine-aspirin, Hydrocodone-acetaminophen (Vicodin), Hydrocodone-ibuprofen (Vicoprofen), Oxycodone-acetaminophen (Percocet),

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Buprenorphine

A 
Partial Opioid Agonist (μ)
Can precipitate mild withdrawl
Can cause analgesia
Partially antagonize effects of morphine
Long-acting
In patch form
Used for maintenance therapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Naloxone

A

Opioid antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Naproxen

A

Non-Selective COX-1 / COX-2 Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Celecoxib

A

COX-2 Selective Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Acetaminophen

A

COX-2 Inhibitor (CNS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ketamine

A

NMDA receptor antagonist

Glutamate antagonist at NMDA receptors in ascending pain pathway blocking acute nociceptive pain

Prevents central sensitization process in chronic pain

Ketamine administration can reduce the development of tolerance to long-term opioid use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Adjuvant analgesics

A

Antidepressants, anticonvulsants

Generally more useful in chronic pain syndromes

17
Q

Migraine – Abortive therapy

A

Ibuprofen, Naproxen, Acetaminophen
Sumatriptan
Dihydroergotamine

18
Q

Dihydroergotamine

A

Ergot Compound

Migraine abortive therapy

19
Q

Sumatriptan

A

5-HT1D Agonist
Migraine abortive therapy
First-line drugs for moderate to severe migraines
Causes cerebral vasoconstriction

20
Q

Migraine – Prophylactic therapy

A 
Beta Blockers
Calcium channel blockers
ACE inhibitors
Anticonvulsants  
Antidepressants
21
Q

Donepezil

A

Cholinesterase inhibitors

Used for dementia

22
Q

Memantine

A

NMDA-glutamate antagonist

Used for dementia

23
Q

Thiamine

A

Wernicke’s encephalopathy

Neuro Pt 2 (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions