Drugs Flashcards

1
Q

Drugs - Falls

A
  • Psychotropics:
    • Sedatives
    • Opiates
    • Antidepressants
  • Antihypertensives
  • Arrhythmia drugs
  • Parkinson’s drugs
  • Antihistamines and night sedatives
  • Long acting sulphonyureas ==> hypos
  • Laxatives
  • Diuretics
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2
Q

Drugs - Dizziness

A
  • Antihypertensives and antianginals ==> hypotension
  • Anticonvulsants
  • Sedatives:
    • Benzodiazepines
    • Antidepressants
    • Major tranquilisers
    • Antibiotics
  • NSAIDS
  • Aspirin - overdose ==> dizziness and tinnitus
  • Codiene/opiate painkillers ==> muzziness or giddyness
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3
Q

Drugs - Alzheimer’s Disease

A
  • All cholinesterase inhibitors => work by increaseing the amount of acetyl choline available in the brain
    • Galantamine (Reminyl)
    • Donepezil (Aricept)
    • Rivastigmine (Exelon)
  • Similar levels of efficacy and SEs
  • Not indicated for vascular dementia - lifestyle modification
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4
Q

Drugs - Delerium (Contributors)

A
  • Anticholinergics (and anticholinergic SEs)
  • Sedatives
  • Opiates
  • Antiparkinsons drugs
  • Analgesics
  • Steroids
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5
Q

Drugs - Parkinson’s Disease

A
  • L-dopa + dopa-decarboxylase 9DDC
    • Co-careldopa (Madopar)
    • Co-beneldopa (Sinemet)
    • Consider adding COMTi - reduces L-dopa breakdown
      • Antacapone
      • Tolcapone (rare)
      • Stavelo - combination
  • MAO-Bi - stops breakdown of endogenous dopamine in synaptic cleft
    • Selegiline
    • Rasagiline
  • Dopamine agonist:
    • Pramipexole
    • Ropinirole
    • Rotigine
  • Amantidine
  • Anticholinergics - sever resting tremor
    • Trihexiphenydril
    • Orphenardrine
  • Late complications - infusions
    • Apomorphine (D1/D2 agonist) - subcutaneous
    • Duodopa (L-Dopa and DDC) via PEG
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6
Q

Drugs - Anticholinergics - Antihistamines (H1-Blockers)

A
  • chlorpheniramine
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7
Q

Drugs - Anticholinergics - Antidepressants

A
  • amitriptyline
  • nortriptyline
  • paroxetine
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8
Q

Drugs - Anticholinergics - Cardiovascular

A
  • furosemide
  • digoxin
  • nifedipine
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9
Q

Drugs - Anticholinergics - Gastrointestinal

A
  • Antidiarrheal Medications
    • atropine
  • Antispasmodic Medications
    • belladonna
    • hycosamine
  • Antiulcer Medications
    • cimetidine
    • ranitidine
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10
Q

Drugs - Anticholinergics - Anti-Parkinson’s

A
  • amantadine
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11
Q

Drugs - Anticholinergics - Muscle Relaxants

A
  • cyclobenzaprine
  • dantrolene
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12
Q

Drugs - Anticholinergics - Anti-Vertigo

A
  • scopolamine
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13
Q

Drugs - Anticholinergics - Antipsychotics

A
  • chlorpromazine
  • clozapine
  • olanzapine
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14
Q

Drugs - Anticholinergics - Urinary Incontinence

A
  • oxybutynin
  • tolterodine
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15
Q

Drugs - Anticholinergics - Phenothiazine Anti-Emetics

A
  • prochlorperazine
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