Drugs Flashcards
1
Q
Drugs - Falls
A
- Psychotropics:
- Sedatives
- Opiates
- Antidepressants
- Antihypertensives
- Arrhythmia drugs
- Parkinson’s drugs
- Antihistamines and night sedatives
- Long acting sulphonyureas ==> hypos
- Laxatives
- Diuretics
2
Q
Drugs - Dizziness
A
- Antihypertensives and antianginals ==> hypotension
- Anticonvulsants
- Sedatives:
- Benzodiazepines
- Antidepressants
- Major tranquilisers
- Antibiotics
- NSAIDS
- Aspirin - overdose ==> dizziness and tinnitus
- Codiene/opiate painkillers ==> muzziness or giddyness
3
Q
Drugs - Alzheimer’s Disease
A
- All cholinesterase inhibitors => work by increaseing the amount of acetyl choline available in the brain
- Galantamine (Reminyl)
- Donepezil (Aricept)
- Rivastigmine (Exelon)
- Similar levels of efficacy and SEs
- Not indicated for vascular dementia - lifestyle modification
4
Q
Drugs - Delerium (Contributors)
A
- Anticholinergics (and anticholinergic SEs)
- Sedatives
- Opiates
- Antiparkinsons drugs
- Analgesics
- Steroids
5
Q
Drugs - Parkinson’s Disease
A
- L-dopa + dopa-decarboxylase 9DDC
- Co-careldopa (Madopar)
- Co-beneldopa (Sinemet)
- Consider adding COMTi - reduces L-dopa breakdown
- Antacapone
- Tolcapone (rare)
- Stavelo - combination
- MAO-Bi - stops breakdown of endogenous dopamine in synaptic cleft
- Selegiline
- Rasagiline
- Dopamine agonist:
- Pramipexole
- Ropinirole
- Rotigine
- Amantidine
- Anticholinergics - sever resting tremor
- Trihexiphenydril
- Orphenardrine
- Late complications - infusions
- Apomorphine (D1/D2 agonist) - subcutaneous
- Duodopa (L-Dopa and DDC) via PEG
6
Q
Drugs - Anticholinergics - Antihistamines (H1-Blockers)
A
- chlorpheniramine
7
Q
Drugs - Anticholinergics - Antidepressants
A
- amitriptyline
- nortriptyline
- paroxetine
8
Q
Drugs - Anticholinergics - Cardiovascular
A
- furosemide
- digoxin
- nifedipine
9
Q
Drugs - Anticholinergics - Gastrointestinal
A
- Antidiarrheal Medications
- atropine
- Antispasmodic Medications
- belladonna
- hycosamine
- Antiulcer Medications
- cimetidine
- ranitidine
10
Q
Drugs - Anticholinergics - Anti-Parkinson’s
A
- amantadine
11
Q
Drugs - Anticholinergics - Muscle Relaxants
A
- cyclobenzaprine
- dantrolene
12
Q
Drugs - Anticholinergics - Anti-Vertigo
A
- scopolamine
13
Q
Drugs - Anticholinergics - Antipsychotics
A
- chlorpromazine
- clozapine
- olanzapine
14
Q
Drugs - Anticholinergics - Urinary Incontinence
A
- oxybutynin
- tolterodine
15
Q
Drugs - Anticholinergics - Phenothiazine Anti-Emetics
A
- prochlorperazine