Drugs Flashcards
1
Q
Warfarin
A
Coumadin (VKA)
- INR goal: 2-3
2
Q
Pradaxa
- Frequency
A
Dabigatran
- # 1 Rec by ACCP. No lab monitoring. No dietary considerations.
- BID
3
Q
Xarelto
- Frequency
A
Rivaroxaban
- No lab monitoring
- No dietary consideration
- QD
4
Q
What is the MOA of:
- Class I
- Class II:
- Class III:
- Class IV:
A
- Class I: Na channe blocker
- Class II: Beta blockers
- Class III: K channel blockers
- Class IV: Ca++ Channel blockers
5
Q
Drugs belong to Class IA:
A
QDAP
- Quinidine
- Disopyramide
- Amiodarone
- Procainamide
=> Atrial & V. arrhythmias
6
Q
Drugs belong to Class IB
A
PM L
- Phenytoin
- Lidocaine
- Mexiletine
=> V. arrhythmias
7
Q
Drugs belong to class IC
A
PMF
- Propafenone
- Moricizine
- Flecainide
=> V. Arrhythmias
8
Q
Drugs belong to class III
A
DAD IS
- Ibutilide
- Amiodarone
- Sotalol
- Dofetilide
- Dronedarone: Multaq
9
Q
Drugs belong to class II
A
BB: rate control
- Esmolol (Brevebloc): short t1/2 => easily reverse
- Propranolol (inderal): 1mg IV; lipid soluble, not B1 selective
- Labetalol
- B1-selective: AMEBBA (Atenolol, Metroprolol, Esmolol, Bisoprolol, Betaxolol, Acebutolol
10
Q
Antidote for BB
A
Glucagon
11
Q
Quinidine
- Indication:
- Therapeutic level:
- ADEs
A
- Quinidine sulfate 83% & Quinidine gluconate 62%
- I: arrhythmias (PO), life threatening malaria (IV)
- Level: 2-5 mcg/mL
- QT prolongation, diarrhea, ringing in the ear, thrombocytopenia
12
Q
Norpace
- Indication:
- ADEs
A
Disopyramide phosphate
- I: ventricular arrhythmia. Use only in life threatening. Incr mortality in non-life threaten
- ADEs: severe anticholinergic, hypoTN, GI
13
Q
Pronestyl
- Active metabolite
- Level
- ADEs
A
Procainamide
- N-acetylprocainamide: NAPA
- Level: 4-10 mcg/mL
- ADEs: Lupus like syndrome, hypoTN, bradycardia, agranulocytosis, diarrhea
14
Q
Xylocaine
- Route
- SE
A
Lidocaine
- 1-5 mcg/mL
- Can only give IM/IV due to poor PO BA
- ADEs: SZ, lightheaded
15
Q
Mexiletine is give PO or IV or IM
A
PO
