Drugs Flashcards
1
Q
SERMs
A
- Tamoxifen
MOA - oestrogen receptor antagonists and partial agonist
Used for - oestrogen receptor positive breast cancer in pre menopausal women
SE - menstrual disturbances, VTE, endometrial cancer
**VTE
2
Q
Aromatase inhibitors
A
- Anastrozole
- Aromatisation accounts for the majority of oestrogen production in post menopausal women
MOA - reduces peripheral oestrogen synthesis
Used for - oestrogen receptor positive breast cancer in post menopausal women
SE - osteoporosis**
3
Q
Trastuzamab
A
- Known as Herceptin
MOA - Monoclonal antibody that blocks HER2
