Drugs Flashcards
Risperidone is used to treat-
Autism
Sleep Problems
BPD
Resperidone can cause what to happen to boys and girls?
Breast development in boys + girls
Resperidone can lead to -
Sexual Dysfunction (Because of Increased Prolactin)
Motor Difficulties
Orthostatic Hypotension
Don’t give Risperidone with-
Lorazepam
Risperidone has been approved for-
Acute Mania
Lurasidone is used to treat -
Bipolar Depression
Side effects of Lurasidone include-
Sedation
Extrapyramidal Symptoms/ EDS (Affected Motor Control + Coordination + Tardive Dyskenesia)
Tardive Dyskenesia is-
A disorder that causes involuntary facial tics after prolonged anti-psychotic use
What should you monitor for Lurasidone?
AIMS
Serum Glucose Levels
Liver Enzymes
Olanzapine is used for -
Schizophrenia
What are the side effects of Olanzapine?
Sedation
Weight Gain
Hyperglycemia
New Onset Type 2 Diabetes
Must monitor Olanzapine for-
New onset type 2 diabetes
Must monitor Olanzapine for-
Excess Sedation
What are the things that you must monitor for in general whenever it comes to 2nd Gen Anti-Psychotics?
Fall Risks
Metabolic Syndrome
Weight Gain
Risk of Stroke for Older PT’s
Amphetamine / Dextroamphetamine is used to treat -
ADHD + Narcolepsy
Atypical Antipsychotics include:
Olanzapine, Risperidone, Risperidone ER, Lurasidone, Paliperidone, Paliperidone ER, Quetiapine
Paliperidone + Paliperidone ER has the same SE and Treatments as-
Risperidone
Clozapine is a last resort due to-
WBC, especially Neutrophil Count
Clozapine treats-
Severely Ill PT’s with Schizophrenia
What should you monitor a PT taking Clozapine for?
Monitor their labs
When can clozapine be prescribed?
PT’s are put on a registry so they can’t take it until they’ve had lab results done
Quetiapine treats-
Bipolar Depression + Sleep Problems
Quetiapine PT’s should be monitored for-
Weight Gain,
Higher risk of Metabolic Syndrome,
Monitor Blood Sugar
Atypical Anti-Psychotics are-
2nd Gen Anti-Psychotics
Name off a buncha Stimulants:
Amphetamine/ Dextroamphetamine, Methylphenidate + Methylphenidate ER, Lisdexamfetamine, Dexmethylphenidate
Amphetamine / Dextroamphetamine treats-
ADHD + Narcolepsy
Amphetamine / Dextroamphetamine SE =
Higher Alertness, BP + HR, Vasoconstriction, Blood Sugar Level
What can long-term or high doses of amphetamines cause?
Heart Problems, Psychosis, Anger
Methylphenidate + Methylphenidate ER has the same SE and Treatment Uses as-
Amphetamine / Dextroamphetamine
Lisdexamfetamine Treats-
ADHD, Binge-Eating Disorder
Lisdexamfetamine SE =
Dry Mouth, Insomnia
Dexmethylphenidate Treats-
ADHD
What should you monitor in a PT taking Dexmethylphenidate?
Seizure, BP + Cardiac Status, Potential Abuse + Dependance on Drug
What lab tests should you expect from a PT taking Dexmethylphenidate?
Periodic CBC, Differential Platelet Counts, Abnormal Liver Function Test (LFT)
Atomoxetine is a-
Non-Stimulant
Atomoxetine is used to treat-
ADHD
Atomoxetine SE =
Lower Appetite, Weight Loss, Fatigue, and Dizziness
What do you need to be able to take Atomoxetine?
Baseline liver function test & enzymes
Atomoxetine is contraindicated for PT’s with-
Why?
Severe Cardiovascular Disease.
Because of it’s potential to raise BP + HR
Aripiprazole is a -
3rd Generation Antipsychotic
Aripiprazole has SE’s that are similar to Risperidone, but name a unique SE that this med has that Risperidone doesn’t.
Unique SE = Orthostatic Hypotension.
Aripiprizole can be used to -
Improve Relatedness, Decrease Anxiety, Compulsive Behaviors, Agitation.
Helps improve irritability that’s expressed in sever temper tantrums, aggression, & self-injurious behavior
1st Generation Anti-Psychotics are-
Typical Anti-Psychotics
What generation of Anti-Psychotics are rarely used?
Typical Anti-Psychotics
Name off some typical anti-psychotics:
Haloperidol, Chlorpromazine, Fluphenazine
Haloperidol is used to treat-
Schizophrenia
What are things that you do for a PT taking Haloperidol?
Why do you do these things?
You keep them hydrated, check their vitals, and test for muscle fragility.
Due to risk of Neuroleptic Malignant Syndrome
What is Neuroleptic Malignant Syndrome?
A life-threatening neurological syndrome caused by anti-psychotics that can cause mental status changes, rigidity, fever, and dysautonomia (Autonomic Processes in the body stop working right)
Chlorpromazine SE =
Very Sedating, Injections can cause pain, Hypotension
Fluphenazine SE =
Higher risk of Extrapyramidal (Drug-Induced Movement Disorders) SE’s + Moderate change in prolactin
What do you monitor in a PT taking Fluphenazide?
Monitor Kidney + Liver Function, BP, and I/O
What is Fluphenazide used for?
Acute + Chronic Psychosis
Typical Anti-Psychotic drugs all cause this symptom:
Causes Shuffling of Feet
A PT taking any of the 3 groups of Anti-Psychotics needs to be monitored for-
A PT taking any of the 3 groups of Anti-Psychotics needs to have what labs monitored?
Parkinson’s-Like Symptoms (Lip-Smacking, Winking, Facial Twitching, Moving Arm Up & Down Involuntarily)
Labs (Liver Enzymes, High Cholesterol, High Blood Sugar)
What is the black box warning for anti-psychotics?
Don’t give to dementia PT’s
If someone is taking anti-psychotics, what precautions do they need to be put on?
Fall Precautions
MAOI’s are-
Not prescribed often
Black Box Warning for Atypical Anti-Psychotics?
Increased risk of dementia-related psychosis in older Pt’s
Black Box Warning for Mood Stabilizers?
Suicide Risk in children and adolescents
Black Box Warning for SNRI’s?
Suicide Risk in children and adolescents from certain antidepressants
Black Box Warning for SSRI’s?
The use of certain anti-depressants to treat Major Depressive Disorder (MDD) in adolescents increases risk of suicidal ideations + behaviors
Black Box Warning for Stimulants?
Potential for Abuse & Diversion (giving drugs out illegally)
What do you need to avoid when taking an SSRI?
NSAID’s, Antiplatelets, Other Anti-Depressants, St John’s Wort
What do you need to avoid when taking a mood stabilizer?
High-Fat Meals (Oils, Chicken Skin, Red Meats + Processed Meats, Dairy, Deep Fried Foods, Avocados, Eggs, Seeds + Nuts)
Caffeine
Bipolar Meds
What do you need to avoid when taking an atypical psychotic?
Grapefruit, Nicotine, Caffeine
Antidepressants, Tricyclic Drugs, Anticholinergic Drugs
What do you need to avoid when taking an SNRI?
MAOI’s
Foods + Drinks High in Caffeine
St. John’s Wort
Weight Loss Drugs
Blood Thinners
Central Nervous System Active Drugs
Advil & Motrin are both -
Ibuprofen
Coumadin & Jantoven are both-
Warfarin
Ibuprofen & Warfarin are both -
Blood Thinners
What do you need to avoid if taking stimulants?
Caffeine (Coffees, Teas, Chocolates, Caffeinated Drinks)
IM Inj is at what degree angle?
90
What are the IM injection sites for kids under 18 months old?
Vastus Lateralis
What are the IM injection sites for kids that are 18 months to 3 years old?
Vastus Lateralis OR Deltoid
These are often used as first-line pharmacotherapy for depression and numerous other psychiatric disorders due to their safety, efficacy, and tolerability =
SSRI’s
What do you need to monitor when a pt takes Duloxetine?
Liver Enzymes
What are the side effects of Tricyclic Antidepressants (TCA’s)?
Dysrhythmias
Heart Block
Tachycardia
Myocardial Infarction
What meds shouldn’t be taken with TCA’s?
MAOI’s
Benzodiazepines
Anti-Hypertensives
Anti-Coagulants
Oral Contraceptives
Abtabuse
Barbiturates
Phenothiazines
What non-med things should a pt taking TCA’s avoid?
Tyramine & Alcohol
Does Fluoxetine have a discontinuation syndrome?
Nah
How can the Vagus nerve be stimulated?
By boosting neurotransmitters (Like Serotonin)
What is stimulation of the Vagus Nerve used for?
Treating Depression
What are the manifestations of Serotonin Syndrome?
Abdominal Pain
Diarrhea
Sweating
Fever
Tachycardia
Hypertension
Delirium
Muscle Spasms
Irritability
Hostility
High Fever
Cardiovascular Shock
Death
When should you watch for Serotonin Syndrome?
When the pt is on Dual Serotonin Enhancing Agents
MAOI’s with SSRI’s are contraindicated
How long should you stop taking an SSRI before taking a MAOI?
2-5 Weeks
Whenever an SSRI dose is rapidly increased, what can occur?
Serotonin Syndrome
What’s the most effective treatment against acute treatment for depression?
Electroconvulsive Therapy
What is Transcranial Magnetic Stimulation (TMS)?
The use of strong magnets to briefly interrupt normal brain activity as a way to study brain regions
If a pt has brain metal implants, this process can’t be undone =
TMS
What herbal treatment messes with all Psychotropic meds?
St. John’s Wort
What meds are used for acute symptoms of anger and violence?
Anti-Anxiety Meds
Anti-Psychotic Meds
What’s the most common Anti-Psychotic used during aggressive or violent incidents?
Haloperidol