Drugs

Question 1

Inducers of CYP450

Answer 1

Carbamzepine
Rifampicin
Barbiturates
Cyclophosphamide
St. John’s wort

Question 2

Inhibitors of CYP450

Answer 2

Cimetidine
Isoniazaid
Grapefruit juice
Pehenelzine
Omeprazole
Ketoconazole
Erythromycin
Retonavir

Question 3

-amil

Answer 3

Calcium channel blockers

Question 4

Barbiturates

Answer 4

Inhibits CNS

Question 5

Omeprazole

Answer 5

Inhibits gastric secretion

Question 6

Isphagula

Answer 6

Bulk laxative

Question 7

Cholestyramine

Answer 7

Sequestration of bile acids

Question 8

Chelating agents?

Answer 8

Dimercaprol
Penicillamine
desferrioxamine

Question 9

Choline esterssd reactivator

Answer 9

Pralidoxime

Question 10

captopril is an

Answer 10

Ace inhibitor

Question 11

Examples of reversible anticholinesterases

Answer 11

neostigmine, physostigmine

Question 12

Allopurinol inhibits what enzyme

Answer 12

Xanthine oxidase

Question 13

Irreversible anticholinesterases eg

Answer 13

organophosphorus compounds (insecticides and war gases)

Question 14

Aspirin inhibits what enzyme and therefore what?

Answer 14

Cox, prostaglandin synthesis

Question 15

Monoamine oxidase inhibitors used to treat depression e.g

Answer 15

Imipramine

Question 16

Proton pump inhibitors: e.g.

Answer 16

Omeprazole

Question 17

quinidine, procainamide are examples of

Answer 17

Sodium channel drugs

Question 18

Examples of calcium channel blockers

Answer 18

nifedipine, verapamil, diltiazem

Question 19

amiodarone, sulfonylureas are?

Answer 19

Potassium channel blockers

Question 20

benzodiazepines act on what channels

Answer 20

Chloride

Question 21

hemicholinium does what

Answer 21

Inhibits choline carrier

Question 22

Inhibition of noradrenaline vesicular uptake by

Answer 22

reserpine

Question 23

Inhibition of neuronal reuptake of noradrenaline

Answer 23

desipramine

Question 24

Inhibition of neuronal reuptake of serotonin

Answer 24

Fluoxetine

Question 25

probenecid

Answer 25

Increases uric acid excretion

Question 26

probenecid inhibits

Answer 26

Weak acid

Question 27

Benzodiazepines do what?

Answer 27

enhance stimulation of gamma-aminobutyric acid (GABA)

Question 28

Dithiocarbamate

Answer 28

Used in nickel and arsenic poisoning as a chelating agent

Question 29

Dithiocarbamate

Answer 29

Used in nickel and arsenic poisoning as a chelating agent

Question 30

EDTA as a chelating agent

Answer 30

Used in Lead poisoning

Question 31

Penicillamine as a chelating agent

Answer 31

Used in copper poisoning

Question 32

Dimecarpol as a chelating agent

Answer 32

Used in Arsenic and mercury poisoning

Question 33

Desferoxamine as a chelating agent

Answer 33

Used in iron poisoning