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Pharmac > Drugs > Flashcards

Drugs Flashcards

1
Q

Inducers of CYP450

A

Carbamzepine
Rifampicin
Barbiturates
Cyclophosphamide
St. John’s wort

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2
Q

Inhibitors of CYP450

A

Cimetidine
Isoniazaid
Grapefruit juice
Pehenelzine
Omeprazole
Ketoconazole
Erythromycin
Retonavir

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3
Q

-amil

A

Calcium channel blockers

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4
Q

Barbiturates

A

Inhibits CNS

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5
Q

Omeprazole

A

Inhibits gastric secretion

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6
Q

Isphagula

A

Bulk laxative

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7
Q

Cholestyramine

A

Sequestration of bile acids

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8
Q

Chelating agents?

A

Dimercaprol
Penicillamine
desferrioxamine

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9
Q

Choline esterssd reactivator

A

Pralidoxime

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10
Q

captopril is an

A

Ace inhibitor

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11
Q

Examples of reversible anticholinesterases

A

neostigmine, physostigmine

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12
Q

Allopurinol inhibits what enzyme

A

Xanthine oxidase

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13
Q

Irreversible anticholinesterases eg

A

organophosphorus compounds (insecticides and war gases)

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14
Q

Aspirin inhibits what enzyme and therefore what?

A

Cox, prostaglandin synthesis

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15
Q

Monoamine oxidase inhibitors used to treat depression e.g

A

Imipramine

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16
Q

Proton pump inhibitors: e.g.

A

Omeprazole

17
Q

quinidine, procainamide are examples of

A

Sodium channel drugs

18
Q

Examples of calcium channel blockers

A

nifedipine, verapamil, diltiazem

19
Q

amiodarone, sulfonylureas are?

A

Potassium channel blockers

20
Q

benzodiazepines act on what channels

21
Q

hemicholinium does what

A

Inhibits choline carrier

22
Q

Inhibition of noradrenaline vesicular uptake by

23
Q

Inhibition of neuronal reuptake of noradrenaline

A

desipramine

24
Q

Inhibition of neuronal reuptake of serotonin

A

Fluoxetine

25
Q

probenecid

A

Increases uric acid excretion

26
Q

probenecid inhibits

27
Q

Benzodiazepines do what?

A

enhance stimulation of gamma-aminobutyric acid (GABA)

28
Q

Dithiocarbamate

A

Used in nickel and arsenic poisoning as a chelating agent

29
Q

Dithiocarbamate

A

Used in nickel and arsenic poisoning as a chelating agent

30
Q

EDTA as a chelating agent

A

Used in Lead poisoning

31
Q

Penicillamine as a chelating agent

A

Used in copper poisoning

32
Q

Dimecarpol as a chelating agent

A

Used in Arsenic and mercury poisoning

33
Q

Desferoxamine as a chelating agent

A

Used in iron poisoning

Pharmac (2 decks)

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