DRUGS

Question 1

Bethanecol

Answer 1

STIMULATES PNS TO INCREASE BLADDER AND RELAX INTERNAL SPINCHTER

HYPOACTIVE BLADDER POST SURGERY POST PARTUM

Question 2

PILOCARPINE

Answer 2

Glaucoma
Stimulates exocrine glands and allows for draining in patients with GLAUCOMA
NEAR VISION
ADVERSE: excessive constriction (Miosis) , loss of accommodation for far vision

Question 3

Pyridostigmine and neostigmine

Answer 3

Inhibit enzyme acetylcholinesterase to stop breakdown of ACH
Treats : mg
Adverse: nausea, vomitting, diarrhea

Question 4

Echothiopate

Answer 4

Inhabits enzyme aceetylcholinesterase to stop breakdown of ACH
Treats:glaucoma (reduce pressure in eye)
Adverse: vomitting, nausea , diarrhea, headaches

Question 5

Donpexzil

Answer 5

Inhibits enzyme acetylcholinesterase to stop breakdown of ACH
Treats: ALZHEIMERS - more ACH is good for memory
Adverse: diarrhea , nausea, vomitting

Indirect cholinergic agonist

Question 6

atropine

Answer 6

Cholinergic ANTAGONIST
Blocks ester cholinergic from binding with muscarinic receptors, prevents parasympathetic effects
Treats: bradycardia ,, low GI AND GU FUNCTION
Adverse: tachycardia, blurred vision, dry mouth

Question 7

TIOTROPIUM

Answer 7

Cholinergic antagonist
Prevents ester choline from binding to muscarinic receptors and turns off parasympathetic effects
Treats COPD - causes bronchodialation
Adverse: tachycardia, dry mouth

Question 8

Dicyclomine

Answer 8

Cholinergic antagonist

Question 9

OXYBUTYNIN

Answer 9

Cholinergic ANTAGONIST
Prevents ester choline from binding with muscarinic receptors to turn off parasympmeffects
Treats: overactive bladder by blocking detrusor contraction
Adverse: urinary retention, dry mouth, nausea

Question 10

SCOPOLAMINE

Answer 10

Cholinergic antagonist
Blocks ester choline from binding with muscarinic receptors and turn odd parasympathetic effects
Treats: motion sickness ; surgical agent “sedation by amnesia”

Question 11

TRIHEXYPHENIDYL

Answer 11

Cholinergic antagonist

Question 12

ATRACURIUM

Answer 12

Cholinergic ANTAGONIST
prevents activation of nicotinic receptors : causes skeletal musical paralysis
Intermediate acting
USED FOR : surgical procedure or mechanical ventilation / intubation
Adverse: respiratory depression, hypertension, arryrhmias

Question 13

PANCURONIUM

Answer 13

Cholinergic antagonist
Prevents activation with nicotinic receptors and therefore causes skeletal muscle paralysis
NONDEPOLARIZING (LONG ACTING0
uses: surgeries / medical intubation and ventilation
Adverse: resp depression, hypertension, arrythmias

Question 14

Succinylcholine

Answer 14

Cholinergic ANTAGONIST
POLARIZING
Acts as ACH agonist that facilitates constant activation that leads to desensitization and prevents skeletal muscle movement
Uses: mechanical intubation/ ventilation
Adverse:prolonged apnea, muscle pain, malignant hyperthermia, hyperkalemia

Question 15

ONABOTULINUMTOXIN A (BOTOX)

Answer 15

CHOLINERGIC ANTAGONIST
inhibits release of ACH at neuromuscular junctions
Used for ; migraines, muscle spasms, excessive sweating
Adverse: local muscle weakness, nausea , headache.

SEMI PERMANENT

Question 16

-OSIN (suffix)

Answer 16

BPH AMD HYPERTENSION

Question 17

-OLOL (suffix)

Answer 17

BETA BLOCKERS
Hypertension, congenital heart failure

Question 18

-IUM (suffix)

Answer 18

ANESTHESIA, MUSCLE PARALYSIS (nondepolarizing)

MEDICAL PROCEDURES
VENTILATION AND INTUBATION