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Anesthesia Drug List > Drugs > Flashcards

Drugs Flashcards

1
Q

What is supplied dose for Etomidate (Amidate) and what is the dosage ?

A

Supplied: 2mg/ml

Dose: 0.2-0.4 mg/kg

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2
Q

What is peak/ onset/ DOA of etomidate?

A

30s| 1 min | 3-10mins

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3
Q

One induction dose of etomidate can cause what ?

A

Adrenal corticosuppression by blocking beta 11 hydroxybuterase

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4
Q

Name side effects of etomidate ?

A

Myoclonus/ epileptic foci/ painful injection / CV stable

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5
Q

How is etomidate metabolized ?

A

Plasma esterase and hepatic enzymes

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6
Q

What is ketamine or Kevelar supplied and dose ?

A

Supplied: 10mg/ml OR 50 mg/ml

Dose: 1-2mg/kg IV or 4-8mg/kg IM

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7
Q

Peak onset and DOA of ketamine?

A

P: 30 sec

Onset: 1 min

DOA: 5-15 mins

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8
Q

Side effects of ketamine

A

Hallucinations
Increased CO and increase in HR
Analgesia
Increased salivation
Decrease in BP

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9
Q

How is ketamine metabolized?

A

By metabolic redistribution

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10
Q

What is the trade name for Methohexital?

A

Brevital

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11
Q

Supplied dose for methohexital?

A

10mg/ml

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12
Q

Dosage for Methohexital?

A

1mg/kg

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13
Q

What is a main contraindication to NOT use Methohexital ?

A

Contraindicated in ASTHMA

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14
Q

What can Methohexital cause ?

A

Porphyria

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15
Q

What is porphyria ? What drug can cause it ?

A

Porphyria is a group of disorders caused by an overaccumulation of porphyrin which helps hemoglobin, the protein that carries oxygen in the blood.

Methohexital can cause this undesired side effect

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16
Q

Peak onset and DOA of Methohexital?

A

P: 30 sec
Onset: 30 sec
DOA: 5-10 mins

Think 30 for 30 ESPN on Methohexital

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17
Q

What is supplied dose of Propofol (Diprivan) ?

A

10mg/ml

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18
Q

How fast does propofol peak ?

A

60 sec

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19
Q

What is onset of propofol?

A

60 sec

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20
Q

What is duration of action for propofol?

A

5-10 mins

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21
Q

Side effects of propofol?

A

Decreases BP

Contraindicated in eggs/ soy allergy

Painful injection

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22
Q

How is propofol metabolized ?

A

Liver and Lungs

23
Q

What is dose supplied for midazolam or versed

A

1mg/ml OR

5mg/ml

24
Q

Dose for midazolam?

A

1-5 mg usually

Or 0.01 - 0.1 mg/kg

25
Q

How fast does midazolam peak?

A

1 minute

26
Q

Onset of midazolam?

A

4 mins

27
Q

DOA of versed or midazolam

A

15-20 mins

28
Q

How is versed metabolized and eliminated ?

A

Renally

29
Q

Side effects of versed

A

Respiratory depression

Amnesia

30
Q

What is half life of midazolam

A

1- 4 hrs

31
Q

Is versed water or lipid soluble ?

A

H20 soluble
Benzodiazepine

32
Q

Supplied dose for precedex (dexmeditomine)

A

200ug/2ml

33
Q

What is loading dose for precedex?

A

1microgram/kg over 10 mins

34
Q

What is maintenance dose for precedex?

A

0.2-0.7 mcg/kg/hr

35
Q

What drug class is precedex?

A

Alpha 2 agonist

36
Q

What is the trade name for succinylcholine ?

A

Anectine

37
Q

Supplied dose for Succs?

A

20mg/ml

38
Q

What type of paralytic is succinylcholine?

A

Depolarizer

Blocks NA channel

Contraindicated in MH

39
Q

What is dose of succs?

A

1-1.5 mg/kg IV

3-4mg/kg IM

40
Q

When does succs peak?

How long does it last?

A

P: 60 secs

DOA: 5-10mins

41
Q

How is succinylcholine metablized?

A

Plasma pseudocholinesterase

42
Q

Mivacurium (Mivacron) supplied dose?

A

2mg/ml

43
Q

What is dosage for mivacurium?

A

0.25mg/kg IV

44
Q

Peak of mivacurium?

A

2-3 mins

45
Q

DOA mivacurium?

A

20-30 mins

Remember to just add zeroes to peak

46
Q

How is mivacurium metabolized?

A

Histamine and plasma cholinesterase

47
Q

What is trade name for atracurium?

A

Tracrium

48
Q

Supplied dose for atracurium?

A

10mg/ml

49
Q

Atracurium desired dosage is what?

A

0.4-0.5 mg/kg

50
Q

When does atracurium peak?

A

3-5 mins

51
Q

What is DOA of atracurium?

A

30-60 mins

52
Q

How is atracurium metabolized?

A

Hoffman hydrolysis and histamine

53
Q

MOA of etomidate?

A

Binds to gaba and Enhances receptor affinity for gaba

It’s a gaba mimetic

54
Q

MOA of Ketamine?

A

Non-competitively binds to NMDA receptor (glutamate) - inhibits glutamate receptor (excitatory) - decreases presynaptic release of glutamate and increases release of GABA

Anesthesia Drug List (1 decks)

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