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IV sedation drugs > drugs > Flashcards

drugs Flashcards

1
Q

Versed
Class
MoA
Effect (3)
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
Metabolism
Half life
reversal
side effects to watch out for
Contraindications

A

Versed (Midazolam)
Class- Benzodiazepine
MoA- INDIRECT GABA agonist
Effect- Anxiolysis, Anterograde Amnesia, Anti-convulsant
onset time- immediate to 5 minutes
duration of action- 1-2 hours
induction dose (if any)- n/a
infusion rate (if any)- n/a
bolus dose (if any)- 1-2 mg preop
Metabolism- Liver
Half life- 2 hours (1.5-2.5)
reversal- Flumazenil .2 mg IV Q15 minutes until reversal seen. max total dose 1mg
side effects to watch out for- respiratory depression in high doses?
Contraindications- over 65 years old, can increase dementia

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2
Q

Lidocaine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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3
Q

Fentanyl
Class
MoA
Effect (1)
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
Metabolism
Half life
reversal
side effects to watch out for (3)
Contraindications

A

Class- Opioid
MoA- Mu receptor agonist
Effect- Analgesia
onset time- 10 seconds
duration of action- 30 min to an 1 hour
induction dose (if any)- n/a
infusion rate (if any)- n/a
bolus dose (if any)- 25-50 mcg per bolus or 1-2 mcg/kg
Metabolism- liver
Half life- 3-7 hours
reversal- Narcan .4 mg every 3 minutes, max dose 3mg
side effects to watch out for- respiratory depression, chest wall rigidity, constipation
Contraindications- n/a

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4
Q

Propofol
Class
MoA
Effect (2)
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
Metabolism
Half life
reversal
side effects to watch out for (4)
Contraindications
Misc: why is it white?

A

Class- sedative
MoA- GABA agonist
Effect- anesthesia, anti-emetic
onset time- 30 seconds
duration of action- 3-10 minutes depending on dose, b/c of fat redistribution prolonged use can prolong duration
induction dose (if any)- 1.5-2.5 mg/kg
infusion rate (if any)- 50-150 mcg/kg/min
bolus dose (if any)- 20 to 30 mg
Metabolism- liver
Half life- 2-24 hours
reversal- time
side effects to watch out for (4)- hypotension, apnea, bradycardia, burns on injection
Contraindications- just watchout for side effects
Misc: Contains Soybean fat emulsion, egg phosphatide, and glycerol

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5
Q

Rocuronium
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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6
Q

Succinylcholine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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7
Q

Ketamine
Class
MoA
Effect (3 major uses, physiologic effects cardiac, blood pressure, respiratory, salivation)
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
Metabolism
Half life
reversal
side effects to watch out for (4)
Contraindications
side effects to watch out for

A

Class- Dissociative anesthetic
MoA- NMDA antagonist (noncompetitive) that blocks glutamate
Effect (3)- anti depressive, analgesic, anesthetic which are dose dependent. Cardiac- increases rate and therefore output, BP- increased, Respiratory- no effect so maintains drive and causes airway relaxation, increase salivation
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
Metabolism- Liver
Half life
reversal
side effects to watch out for (4)
Contraindications

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8
Q

Dexamethasone
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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9
Q

Ondansetron
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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10
Q

Epinephrine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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11
Q

Phenylephrine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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12
Q

Ephedrine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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13
Q

Glycopyrrolate
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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14
Q

Atropine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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15
Q

Neostigmine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
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16
Q

Sugammadex
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
17
Q

Hydralazine
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
18
Q

Precedex (dexmetatomadine)
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
19
Q

Dilauded
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
20
Q

Remifentanyl
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
21
Q

Esmolol
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
22
Q

Labetalol
Class
MoA
onset time
duration of action
induction dose (if any)
infusion rate (if any)
bolus dose (if any)
reversal
side effects to watch out for

A
23
Q
A

IV sedation drugs (2 decks)

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