drugs

Question 1

patient what would you prescribe to a patient having syncope episode and postural hypotension as a side effect of levodopa

Answer 1

Fludrocortisone

Question 2

what is fludrocortison
indication
side effects
dosage

Answer 2

corticosteroid classically used a synthetic mineralocorticoid to replace low levels of aldosterone. It is also used in orthostatic (‘postural’) hypotension as an alternative to midodrine, which has some significant side-effects (BPH and hypertension) in certain patients

for postrual hypotension - 100-400mg
for adrenocortical insufficiency - 50- 300mg OD

Question 3

midodrine
class and mechanism of action
dose and indication
caution

Answer 3

alpha 1 agonist
it is a vasopressor/antihypotensive agent.
acts on peripheral alpha-adrenergic receptors to increase arterial resistance, resulting in an increase in blood pressure.

dose: 2.5mg three times a day
indication : postural hypotension
caution with : Aortic aneurysm; blood vessel spasm; bradycardia; cardiac conduction disturbances

Question 4

enoxaparin and dalteparin

Answer 4

low molecular weight heprin used for vte prophylaxis

Question 5

fibrinolytic

Answer 5

streptokinase, alteplase and tenecteplase.

Question 6

drug treatment for wpw

Answer 6

sotalol, amiodarone, flecainide

Question 7

Side effects of beta blockers

Answer 7

• sleep disturbances
• erectile dysfunction
• broncospasm
• cold peripheries
  -fatigue

Question 8

contraindication of beta blockers

Answer 8

• uncontrolled HF
• asthma
  -sick sinus syndrome
  -concurrent verapamil use: may precipitate severe bradycardia
  -second or third degree heart block

Question 9

Hydralazine

Answer 9

vasodilator

Question 10

pci with radial vs femoral access
anti-platlets

Answer 10

femoral access:
bivalirudin with bailout GPI

radial access
infracturated heprin +gpi

Question 11

dronedarone

Answer 11

maintain sinus rhythm in patients with a history of atrial fibrillation following cardioversion

Question 12

flecainide

Answer 12

antiarrhythmic drug (AAD) which blocks cardiac Na+ channels

Question 13

Indications for a temporary pacemaker

Answer 13

symptomatic/haemodynamically unstable bradycardia, not responding to atropine
post-ANTERIOR MI: type 2 or complete heart block*
trifascicular block prior to surgery