Drugs Flashcards

1
Q

What type of drug is reserpine?

A

α-adrenergic inhibitor. Depletes monoamine neurotransmitter. Used for depression and hypertension

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2
Q

What type of drug is iproniazid?

A

MAO inhibitor. Used as an antidepressant

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3
Q

What type of drug is phenelzine?

A

MAO inhibitor. Used for severe depression and bipolar disorder

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4
Q

What type of drug is moclobemide?

A

MAO inhibitor. Used for depression

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5
Q

What type of drug is imipramine?

A

Tricyclic antidepressant. Blocks monoamine uptake. Used for depression

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6
Q

What type of drug is fluoxetine/prozac?

A

SSRI. Displaces serotonin transporters. Used for depresison

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7
Q

What type of drug is citalopram?

A

SSRI. Displaces serotonin transporters. Used for depression

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8
Q

What type of drug is reboxetine?

A

Noradrenaline reuptake inhibitor. Used for depression

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9
Q

What type of drug is LSD?

A

Serotonin receptor agonist.

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10
Q

What type of drug is lithium for bipolar disorder?

A

Permeates voltage gated Na channels. Inhibits inositol monophosphate, preventing AKT signalling

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11
Q

What type of drugs are amphetamines?

A

Displaces DA and NA vesicles. Used for ADHD and narcolepsy

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12
Q

How does cocaine function as a drug?

A

Inhibits dopamine transporters and nerve terminals. Local anaestetic

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13
Q

How does ketamine acts as a drug?

A

Blocks NDMA receptors. Dissociative anaestetic

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14
Q

What type of drug is phencyclidine?

A

Dopamine blocker. Intravenous anaestetic

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15
Q

What type of drug is chlopromazine?

A

Dopamine receptor antagonist. Antipsychotic

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16
Q

What type of drug is clozapine?

A

Restores neurotransmitter levels. Used for schizophrenia

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17
Q

What type of drug is diazepam?

A

GABAa postitive allosteric modulator. Used as an anti-anxiolytic

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18
Q

What types of drug are vigabatrin and valproate?

A

GABA transaminases. Was used for epilepsy. Valproate has vertigo and ataxia side effects.

19
Q

What type of drug is ethosuximide?

A

3-Ca2+ channel blocker. Used for absence seizures (petit mal)

20
Q

What sort of drug is pregabalin

A

4-Ca2+ channel blocker. Binds to its α-subunit to prevent it inserting into the synaptic membrane. Also inhibits glutamate vesicles. Used for epilepsy

21
Q

What sort of drug is muscismol?

A

GABAa orthosteric agonist

22
Q

What sort of drug is Bicuculline?

A

GABAa orthosteric antagonist

23
Q

What sort of drug is picrotoxin?

A

GABAa orthosteric antagonist

24
Q

What sort of drug is flumazenil?

A

GABAa NAM

25
Q

What sort of drug is zolpidem?

A

GABAa PAM

26
Q

What sort of drug is propranolol?

A

β2 adrenergic receptor antagonist. Anxiolytic

27
Q

What sort of drug is bispirone?

A

SSRI for anxiety

28
Q

What sort of drug is nitric oxide?

A

NDMA receptor blocker. Used as an inhaled anaestetic

29
Q

What sort of drug is isofluorane?

A

Halogenated hydrocarbon. Used as an inhaled anaestetic

30
Q

What sort of drug is thiopental?

A

Barbiturate. Used as an anaestetic

31
Q

What sort of drug is etomidate?

A

Aminobutryic acid type A receptor PAM. Anaestetic

32
Q

What sort of drug is dantrolene?

A

Ryanodine receptor inhibitor. Used as an anaestetic

33
Q

What sort of drug is morphine?

A

Mu opiate receptor agonist

34
Q

What sort of drug is heroin?

A

Opiate

35
Q

What sort of drugs aspirin and ibuprofen?

A

NSAID. COX 1 and 2 inhibitor

36
Q

What sort of drug is rofecoxib?

A

COX-2 inhibitor

37
Q

What sort of drug is misoprostol?

A

Synthetic prostaglandin. for treating gastric ulcers

38
Q

What sort of drug is methotrexate?

A

DMARD. Folic acid antagonist. Used for rheumatoid arthritis

39
Q

What sort of drug is sulfasalazine?

A

DMARD. Treatment for rheumatoid arthritis

40
Q

What sort of drug is cyclosporin?

A

Steroid. Inhibits IL-2 transcription. Treatment for rheumatoid arthritis

41
Q

What sort of drug is adalimumab?

A

Monoclonal antibody anti-inflammatory

42
Q

What sort of drug is salbutamol?

A

Bronchodilator. Asthma treatment

43
Q

What sort of drug is prednisolone?

A

Steroid. IL-2 inhibitor for chronic inflammation

44
Q

What does tiagabine do?

A

Inhibits GABA uptake
Anti-convulsant