Drugs Flashcards

1
Q

What type of drug is reserpine?

A

α-adrenergic inhibitor. Depletes monoamine neurotransmitter. Used for depression and hypertension

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2
Q

What type of drug is iproniazid?

A

MAO inhibitor. Used as an antidepressant

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3
Q

What type of drug is phenelzine?

A

MAO inhibitor. Used for severe depression and bipolar disorder

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4
Q

What type of drug is moclobemide?

A

MAO inhibitor. Used for depression

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5
Q

What type of drug is imipramine?

A

Tricyclic antidepressant. Blocks monoamine uptake. Used for depression

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6
Q

What type of drug is fluoxetine/prozac?

A

SSRI. Displaces serotonin transporters. Used for depresison

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7
Q

What type of drug is citalopram?

A

SSRI. Displaces serotonin transporters. Used for depression

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8
Q

What type of drug is reboxetine?

A

Noradrenaline reuptake inhibitor. Used for depression

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9
Q

What type of drug is LSD?

A

Serotonin receptor agonist.

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10
Q

What type of drug is lithium for bipolar disorder?

A

Permeates voltage gated Na channels. Inhibits inositol monophosphate, preventing AKT signalling

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11
Q

What type of drugs are amphetamines?

A

Displaces DA and NA vesicles. Used for ADHD and narcolepsy

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12
Q

How does cocaine function as a drug?

A

Inhibits dopamine transporters and nerve terminals. Local anaestetic

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13
Q

How does ketamine acts as a drug?

A

Blocks NDMA receptors. Dissociative anaestetic

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14
Q

What type of drug is phencyclidine?

A

Dopamine blocker. Intravenous anaestetic

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15
Q

What type of drug is chlopromazine?

A

Dopamine receptor antagonist. Antipsychotic

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16
Q

What type of drug is clozapine?

A

Restores neurotransmitter levels. Used for schizophrenia

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17
Q

What type of drug is diazepam?

A

GABAa postitive allosteric modulator. Used as an anti-anxiolytic

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18
Q

What types of drug are vigabatrin and valproate?

A

GABA transaminases. Was used for epilepsy. Valproate has vertigo and ataxia side effects.

19
Q

What type of drug is ethosuximide?

A

3-Ca2+ channel blocker. Used for absence seizures (petit mal)

20
Q

What sort of drug is pregabalin

A

4-Ca2+ channel blocker. Binds to its α-subunit to prevent it inserting into the synaptic membrane. Also inhibits glutamate vesicles. Used for epilepsy

21
Q

What sort of drug is muscismol?

A

GABAa orthosteric agonist

22
Q

What sort of drug is Bicuculline?

A

GABAa orthosteric antagonist

23
Q

What sort of drug is picrotoxin?

A

GABAa orthosteric antagonist

24
Q

What sort of drug is flumazenil?

25
What sort of drug is zolpidem?
GABAa PAM
26
What sort of drug is propranolol?
β2 adrenergic receptor antagonist. Anxiolytic
27
What sort of drug is bispirone?
SSRI for anxiety
28
What sort of drug is nitric oxide?
NDMA receptor blocker. Used as an inhaled anaestetic
29
What sort of drug is isofluorane?
Halogenated hydrocarbon. Used as an inhaled anaestetic
30
What sort of drug is thiopental?
Barbiturate. Used as an anaestetic
31
What sort of drug is etomidate?
Aminobutryic acid type A receptor PAM. Anaestetic
32
What sort of drug is dantrolene?
Ryanodine receptor inhibitor. Used as an anaestetic
33
What sort of drug is morphine?
Mu opiate receptor agonist
34
What sort of drug is heroin?
Opiate
35
What sort of drugs aspirin and ibuprofen?
NSAID. COX 1 and 2 inhibitor
36
What sort of drug is rofecoxib?
COX-2 inhibitor
37
What sort of drug is misoprostol?
Synthetic prostaglandin. for treating gastric ulcers
38
What sort of drug is methotrexate?
DMARD. Folic acid antagonist. Used for rheumatoid arthritis
39
What sort of drug is sulfasalazine?
DMARD. Treatment for rheumatoid arthritis
40
What sort of drug is cyclosporin?
Steroid. Inhibits IL-2 transcription. Treatment for rheumatoid arthritis
41
What sort of drug is adalimumab?
Monoclonal antibody anti-inflammatory
42
What sort of drug is salbutamol?
Bronchodilator. Asthma treatment
43
What sort of drug is prednisolone?
Steroid. IL-2 inhibitor for chronic inflammation
44
What does tiagabine do?
Inhibits GABA uptake Anti-convulsant