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Fucking Hell > Drugs > Flashcards

Drugs Flashcards

1
Q

Amphetamine

A

Mixed salts (Adderall),
dexamphetamine,
lisdexamphetamine

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2
Q

Methylphenidate

A

Ritalin
Concerta

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3
Q

Atomoxetine

A

Ne>serotonin>dopamine

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4
Q

Guanfacine

A

Lowers Blood pressure
ADHD

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5
Q

Benzo for anxiety

A

Diazepam
Xanax: GAD, Panic
Ativan: surgery

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6
Q

Citalopram

A

SSRI; PDA, SAD

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7
Q

Escitalopram

A

SSRI; all

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8
Q

Prozac

A

Fluoxetine, SSRI; panic only

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9
Q

Fluvoxamine

A

SSRI; panic and social

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10
Q

Paroxetine

A

SSRI; all

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11
Q

Sertraline

A

SSRI; all

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12
Q

Duloxetine

A

SNRI; GAD only

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13
Q

Venlafaxine

A

SNRI; all

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14
Q

Buspirone

A

Anxiety: GAD
Presynaptic 5-HT1A agonist,
D2 antagonist.

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15
Q

Apo-clomipramine

A

Tricyclic antidepressant

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16
Q

Depression - MOAI

A

Nardil
Pamate
Menerix

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17
Q

Anxiety

A
  1. Benzo
  2. SSRI & SNRI
  3. Buspirone
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18
Q

ADHD

A
  1. Amphetamine
  2. Metheylphenidate
  3. Atomoxetine
  4. Guanfacine
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19
Q

Bipolar Disorder

A
  1. Anticonvulsant
  2. Atypical antipsychotics
  3. Antidepressant
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20
Q

Valoproate

A

Anticonvulsant - Bipolar disorder
GABA increase

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21
Q

Lamotrigine

A

Anticonvulsant, bipolar disease
Glutamate decrease

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22
Q

Carbamazepine

A

Anticonvulsant; bipolar

23
Q

Lithium

A

Anticonvulsant; bipolar
- antioxidant defense
- increase GABA
- inhibit DA and GLU
- increase grey matter

24
Q

Olanzapine

A

Bipolar disorder
Rapid

25
Q

Quetiapine

A

Bipolar disorder
Acute mania and depressjon

26
Q

Anticonvulsant for
Bipolar Disorder

A
  1. Valproate
  2. Lamotrigine
  3. Carbamazepine
  4. Lithium
27
Q

Atypical Antipsychotics for
Bipolar Disorder

A
  1. Olanzepine
  2. Quetiapine
28
Q

Schizophrenia

A
  1. Typical antipsychotics
  2. Atypical antipsychotics
29
Q

Typical antipsychotics

A
  1. Chlorpromazine
  2. Haloperidol
  • positive symptoms
  • extrapyramidal effect
  • neuroleptic malignant syndrome
  • peolactin release
30
Q

Atypical antipsychotics
For schizophrenia

A
  1. Clozapine
  2. Quetiapine
  3. Aripiprazole (3rd gen)
31
Q

Epilepsy

A
  1. Modulation of votage gated ion channels
  2. Inhibition of synaptic excitation: inhibit Glutamate
  3. Enhancement of synaptic inhibition: increase GABA
32
Q

Epilepsy:
Modulation of votage gated channels

A
  1. Inhibition of Na+ channel
    - phenytoin
    - carbamazepine
    - valproic acid
    - topiramate
  2. Inhibition of T-type Ca2+ channel
    - ethosuximude
  3. K+ channel activation
33
Q

Epilepsy
2. Inhibition of synaptic excitation: glu

A

Inhibit
1. L-type Ca2+: gabapentine

  1. SV2A : levetiacetam, brivaracetam
  2. AMPA or kainate: perampanel, topiramate
34
Q

Epilepsy
3. Enhancement of synaptic inhibition: GABA

A
  1. PAM of GABA: benzo, barbi, topiramate!
  2. Inhibition of GABA-T: vigabatrin (blindness)
35
Q

Migraine

A
  1. 5-HT1 receptor agonist
  2. NSAIDs
  3. CGRP ab
36
Q

Migraine drugs:
1. 5-HT1 agonist

A
  1. Ergot Alkaloids - ergotamine
  2. Triptan - sumatriptan, zolmitriptian
37
Q

NSAIDs

A

Arachidonic acid - prostagladin - //- prostanoid (COX-1 or COX-2) mediated

38
Q

CGRP

A

Binds CLR/RAMP1 , NO production and glutamate increase — vasodilation, pain

39
Q

CGRP drug - ab

A

Erenumab - ab for CGRP receptor
Galcanezumab - ab for CGRP

40
Q

Alzheimers Disease

A
  1. NMDA antagonist; memantine
  2. Anti-AChE
    - donepezil
    - galantamine
    - rivastigmine
  3. Antibody for beta-amyloid
    - aducanumab
41
Q

Parkinsons disease
1. L- DOPA (+)
2. Dopamine agonist
3. MAO-B inhibitor

A
  1. L Dopa,
    carbidopa,
    entacapone
  2. Pramipexole
    Ropinirole
    Apomorphine
  3. Selegiline
    Rosagiline
42
Q

Barbiturates

A
  1. Phenobarbitaturate: tonic-clonic
  2. Pentobarbital- animal euthanasia
43
Q

Benzodiazepine

A
  1. Short acting
    - xanax
    - ativan
    - flunitrozepam
  2. Long acting: diazepam
  3. Z drugs
    - zolpidem
    - zolpiclone
44
Q

Opioids

A

Morphine, codeine, oxycodone, fentanyl

45
Q

Opioid overdose drug

A
  1. Acute: narcan - mu antagonist
  2. Chronic:
    - buprenorphine (partial agonist
    - methadone (full agonist
    - naltrexone (competitive antagonist
46
Q

Alcohol abuse treatment

A

Diazepam
Acamprosate
Naltrexone

47
Q

Diazepam

A

Benzodiazepine.
Anxiolytic, anticonvulsant

Acute alcohol withdrawal symptom

48
Q

Quetiapine

A

Atypical antipsychotic.
Bipolar disorder
Schizophrenia

49
Q

Topiramate

A

All epilepsy treatment

50
Q

Naltrexone

A

Opioid chronic abuse treatment ( mu competitive antagonist)

Alcohol restraint in NAc and VTA

51
Q

Carbamazepine

A

inhibit Na+ channel
Anticonvulsant in Bipolar disorder
Epilepsy

52
Q

Status epilepticus

A

Epilepsy 5 min

53
Q

Migraine

A

Premonitory, aura, headache, postdrome

54
Q

Neuroleptic malignant syndrome

A

Increased heart rate
Typical antipsychotics side effect

Fucking Hell (1 decks)

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