Drugs Flashcards
Monitoring required for SNRIs
Blood pressure
What patients who start taking citalopram require an ECG
Those with existing cardiac hx
Risk of prolonged QT
In high risk patients what should be monitored before starting and every 3 months when taking citalopram
U&Es
Risk of hyponaterima
Most common side effects of TCAs (the 3 groups)
Anticholinergic: Dry mouth Blurred vision Drowsy Constipation urinary retention
Antiadrenergic: hypotension
Antihistamine: drowsy
5 dangerous side effects os SSRI
SIADH Suicide UGI bleeds QTC prolonged (anti depressant discontinuation syndrome)
Which opiod has effect on serotonin receptors and can cause SS
Tramadol
triptans and ondansetron too
A patient is on tramadol, sertraline and ondansetron, what are they at high risk of
Serotonin syndrome
TCA name ending
-pramine
=-triptlyine
Other than side effects, why are TCAs used less
Dangerous in OD (broad complex tachycardia)
When is mitrazapine given
At night - drowsy
Key risk of MAOIs and RIMAs
Hypertensive crisis so cannot eat tyramine
What happens if a patient misses more than 2 clozapine doses
Restart starting regime
3 drugs that are contraindicated with lithium
NSAIDs
ACEi
Diuretics
Due to the renal excretion
Why may long term antipsychotic use result in oliguria
Insulin resistance
DM
Polyuria/ polydipsia
Action if a patient on lithium has raised WBC
Nothing - normal response