Drugs

Question 1

Succinylcholine

Answer 1

depolarizer

1mg/kg

Question 2

Atracurium

Answer 2

nondepolarizer
0.6 mg/kg induction
histamine release/hoffmann

Question 3

Cisatricurium

Answer 3

nondepolarizer
0.1 mg/kg induction
Hoffmann

Question 4

Mivacurium

Answer 4

nondepolarizer
0.15 mg/kg induction
histamine release

Question 5

Pancuronium

Answer 5

nondepolarizer/steroidal
0.08 mg/kg
most potent, long acting, vagolytic

Question 6

Vecuronium

Answer 6

nondepolarizer/steroidal

0.1 mg/kg

Question 7

Rocuronium

Answer 7

nondepolarizer/steroidal
0.6 mg/kg
least potent, fastest onset

Question 8

Steroidal NMBD

Answer 8

account for liver/kidney dysfunction, may need to lower dose
Vec & Roc can only use sugammadex for reversal

Question 9

Endogenous Histamine

Answer 9

decrease arterial BP, increase HR and myocardial contractility, increase capillary permeability, and H1 constricts bronchiolar smooth muscle

Question 10

Endogenous Serotonin

Answer 10

powerful vasoconstrictor, vasodilate at the heart, increased airway resistance, GI release of Ach in myenteric plexus to increase peristalsis

Question 11

5 N/V receptor types

Answer 11

Serotonin, Dopamine, Muscarinic, Histamine and NK-1

Question 12

Glycogenolysis & Gluconeogenesis

Answer 12

breakdown of glycogen into glucose
creation of glucose from glycogen
Both stimulated by glucagon

Question 13

Glycolysis

Answer 13

breakdown of glucose to generate energy

Question 14

Ondansetron (zofran)

Answer 14

5-HT3 Serotonin
4 mg IV single dose
0.1 mg/kg peds if <40kg

Question 15

Droperiodol

Answer 15

Dopamine

0.625-1.25 mg IV slow push

Question 16

Metoclopramide (reglan)

Answer 16

Dopamine

10 mg IV slow d/t abd cramping

Question 17

Prochlorperazine (Compazine)

Answer 17

Dopamine

5-10 mg IV

Question 18

Aprepitant (Emend)

Answer 18

NK-1

40-80 mg IV

Question 19

Dexamethasone (Decadron)

Answer 19

Corticosteroid
4-10mg IV
0.2-0.5 mg/kg IV peds >3 yrs old

Question 20

Dimenhydrinate (Drammamine)

Answer 20

H1 blocker

50-100 mg IV/IM Q4hrs

Question 21

Promethazine (Phenergan)

Answer 21

H1 blocker

6.25-25 mg IM, IV associated with tissue necrosis

Question 22

scopolamine

Answer 22

antimuscarinic

1.5 mg patch 2 hours prior to surgery or evening before

Question 23

midazolam PONV

Answer 23

2 mg IV

50-75 mcg/kg IV peds

Question 24

ephedrine

Answer 24

10-25 mg IV only for postural hypotension induced N/V

Question 25

physostigmine

Answer 25

0.01-0.03 mg/kg IV

reversal for scopolamine overdose

Question 26

gabapentin for PONV

Answer 26

600-800 mg PO prior to surgery

Question 27

glycopyrrolate

Answer 27

0.01-0.02 mg/kg

Question 28

neostigmine

Answer 28

0.06-0.08 mg/kg

Question 29

atropine

Answer 29

0.015 mg/kg

Question 30

endrophonium

Answer 30

1-1.5 mg/kg IV

Question 31

Hydrocortisone supplementation doses based on case

Answer 31

minor: 25 mg IV
moderate: 50-75 mg IV
major: 100-150 mg IV

Question 32

Patients who require corticosteroid supp

Answer 32

take greater than 5 mg of prednisone equivalent daily
2-3 weeks or longer of corticosteroid treatment
tx occurred during immediate 12 months before surgery

Question 33

Tx of adrenal crisis

Answer 33

hydrocortisone 100 mg IV and fluids

Question 34

Adrenal Crisis S/S

Answer 34

Fever, hyponatremia, hyperkalemia, hypoglycemia, and hypercalcemia
hypotension sys <100 or reduction greater than 20 mmHg, abd symptoms, n/v, altered mental status, fatigue

Question 35

Midazolam induction dose

Answer 35

0. 02-0.04 mg/kg IV

0. 4-.08 mg/kg PO peds

Question 36

Lidocaine induction dose

Answer 36

1 mg/kg

Question 37

fentanyl induction dose

Answer 37

1-3 mcg/kg

Question 38

propofol induction dose

Answer 38

1.5-2.5 mg/kg

Question 39

ketamine periop dose for surgical sitm

Answer 39

0.5-1 mg/kg

Question 40

sugammadex reversal for roc or vec

Answer 40

2 mg/kg >2 twitches
4 mg/kg 1-2 twitches
deep block 16 mg/kg 0 TOF