Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Block 3 test 3 > Drugs > Flashcards

Drugs Flashcards

1
Q

Epinephrine affinity

A

B1 and B2 then alpha at higher doses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Epinephrine indications

A

anaphylactic shock

complete heart block

cardiac arrest

Prolonged Anestetic actions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Adverse affects of Epinephrine

A

HTN, cerebral hemmorage and arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Low dose effect (graph of epi)

A

up: pulse (B1)

Down: peripheral resistance (B2)

Increase in sys (B1)

Decrease in diastolic (B2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Epinephrine Reversal

A

Higher dose epi= pressor

Given w/ alpha antagonist =decrease in pressure. Due to unopposed beta activity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

NE affinity

A

Alpha 1 and alpha 2 > B1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

NE lacks affinity for

A

B2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

NE acts how

A

Potent vasoconstrictor.

Increases CO.

HR may decrease slightly due to baroreceptor reflex.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

NE indications

A

Hypotension , shock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

AEs of NE

A

High risk of HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

NE trace

A

Lowers heart rate: (baroreceptors)
Up: Peripheral resistance (unopposed alpha 1 effect)

Overall increase in MAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dopamine affinity

A

Low (D1): vasodilation in renal , mesenteric, and coronary beds.

Moderate (B1):

High (Alpha)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Dopamine indications

A

shock and heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dopamine AEs

A

Similar to NE… .HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Phenylephrine affinity

A

alpha 1 –vasoconstriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Phenylephrine indications

A

hypotension/shock

nasal congestion

mydriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Phenylephrine AEs

A

reflex Brady cardia due to vasoconstriction . Has no direct effects on heart, so use when you don’t want to induce tacky

18
Q

Clonidine affinity

A

Alpha 2 agonist in CNS . Decreases SNS outflow from CNS and decreases NE release.

19
Q

Clonidine indications

A

HTN, addiction , post menopausal hot flashes

20
Q

Brimonidine affinity

A

Alpha 2 agonist -topical use to treat glaucoma.

21
Q

Dobutamine affinity

A

B1 (B2>alpha)- increases contractile strength . . more than in increases rate

Indications: cariogenic shock and heart failure

22
Q

Isoproterenol affinity

A

Nonselective beta agonist

23
Q

Isoproterenol indications

A

infrequently used for complete heart block. Cardiac arrest.

24
Q

Isoproterenol AEs

A

Arrythmia

25
Q

Albuterol, Metaproterenol, terbutaline

A

B2 agonist

26
Q

Albuterol, Metaproterenol, terbutaline indications

A

bronchodilation asthma , COPD,, can also be used to relax the uterus to inhibit premature labor.

27
Q

Isoproternol trace

A

Pulse: increase (B1 + baro-reflex)
PR: decrease (B2)
MAP: inchanged(diastolic decrease and systolic increase)

28
Q

Initital vasopressor of choice with septic shock, cardogenic shock, and hypovolemic shock

A

NE

29
Q

Initial vasopressor when tachyarrythmias preclude use of NE

A

Phenylephrine

30
Q

Alternative to NE in septic shock in highly selected patients (compromised systolic function or bradycardia and a low risk of tachyarrthmias).

A

Dopamine

31
Q

Initial agent of choice with low CO and maintained blood pressure.

A

Dobutamine

32
Q

Mirabegron mechanism

A

relaxes bladder detrusor muscle .

33
Q

Ephedrine mechanism

A

alpha , B1 and B2 affinity . . .

Increases NE release . CNS stimulant

34
Q

AMphetamine

A

increase NE and DA from storage vesicles.

35
Q

Cocoaine

A

blocks NE and Epi reuptake also blocks DAT and SERT

36
Q

MDMA

A

increases serotonin release. Blocks NET, DAT, SERT release.

37
Q

Phenoxybenzamine vs Phentolamine

A

Phenoxy: long acting . Irreversible. Can cause hypotension or relfextachy .

Phentolamine : short acting . Competitive. Can cause hypotension or reflex tacky

38
Q

Alpha 1 blocker for HTN

A

prazosin

39
Q

A 1 blocker for HTN and BPH

A

Terazosin

40
Q

A 1 blocker for BPH only

A

Tamsulosin

Block 3 test 3 (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions