Drug Therapy for: Diarrhea

Question 1

Diphenoxylate with Atropine (Lomotil): What kind of diarrhea is treated?

Answer 1

moderate to severe

Question 2

Diphenoxylate with Atropine (Lomotil): Action

Answer 2

slows peristalsis by action on intestinal smooth muscle

Question 3

Diphenoxylate with Atropine (Lomotil): a/e

Answer 3

• tachycardia
• flushing
• dry skin and mucous membranes
• urinary retention

Question 4

Diphenoxylate with Atropine (Lomotil): Administration is ___.

Answer 4

oral

Question 5

Diphenoxylate with Atropine (Lomotil): When should I stop taking it?

Answer 5

once diarrhea is under control stop taking lomotil immediately

Question 6

Diarrhea drug teaching: Are there any special diet restrictions I should know about?

Answer 6

• yes, avoid highly spiced foods and laxative type foods and beverages: fresh fruits and vegetables, coffee/caffeinated and noncarbonated beverages

Question 7

Diarrhea drug teaching: I’m taking lomotil or imodium are there any special precautions for these drugs?

Answer 7

Yes, they can cause dizziness or drowsiness so use caution if driving or task requiring high alertness, coordination or physical dexterity. Also avoid alcohol or other drowsy causing drugs.

Question 8

Diarrhea drug teaching: I’m taking Pepto-Bismo and my poop is a weird color, is that normal?

Answer 8

If it looks grayish-black yes but it’s temporary.

Question 9

Diarrhea drug teaching: My mouth is so dry after taking lomotil, is that normal?

Answer 9

Yes sucking on hard candy or chewing gum may help this a/e.

Question 10

Diarrhea drug teaching: I am thinking about taking Pepto-Bismol but what is the difference between the liquid and tablet form?

Answer 10

Liquid = shake it well before measuring your dose
Tablet = chew it well or let it dissolve in your mouth

Question 11

Loperamide (Imodium): action

Answer 11

increases GI motility by effect on intestinal muscles

Question 12

Loperamide (Imodium): a/e

Answer 12

• ab pain
• constipation
• fatigue
• n/v

Question 13

Loperamide (Imodium): Clinically when should admin be stopped?

Answer 13

After 48-hours if improvement has not occurred

Question 14

Loperamide (Imodium): Overdose is treated by

Answer 14

• naloxone
• gastric lavage
• activated charcoal

Question 15

Bismuth Subsalicylate (Pepto-Bismol): What effects does it posses because of its salicylate component?

Answer 15

antisecretory and possible anti inflammatory effects

Question 16

Bismuth Subsalicylate (Pepto-Bismol): a/e

Answer 16

darkening of the tongue or stool its harmless and temporary because of the salt