Drug Terms Flashcards
Chronotropic (chrono-time)
Affecting regularity or rate (- decreases, + increases)
Inotropic (Ino - fiber)
Affecting force of muscle contraction (- weakens, + strengthens)
Alpha Adrenergic Receptors location?
Peripheral Vasculature
Alpha 1 receptor
Vasoconstrictive
+ Inotropic, - Chronotropic
Alpha 2 receptor
Vasoconstrictive prevents nor-epi release
Beta - Adrenergic Receptor Locations?
Beta -1 Heart Beta -2 Lung
Beta -1
Heart + Chronotropic + Inotropic
Beta -2
Lungs
Vasodilation
Bronchodilation
Dopaminergic Receptors
Ace -Inhibitor (Mech of Action)
Blocks Angio I to Angiotensin II (which is vasoconstrict) Decreases periph arterial reisistence Decreases alosterone secretion Promotes sodium/h20 secrection Lowers BP Decreases afterload (SVR) and Preload
Ace - Inhibitors (drugs)
Captopril Enalapril Lisinopril
Ace-Inhibitors (side effects)
- Decrease BP
- Increase HR
- Angina
- Cough
- Increase K
ARBS
(Angiotension II Receptor Antagonists)
- Blocks aldosterone secretion effect of Angiotensin II
- Blocks Vasoconstriction effect
- Supports cardiac remodeling
ARBS (DRUGS)
Irbesartan (Avapro)
Losartan (Cozaar)
Valsartan (Diovan)
Ace Inhibitor (Indications)
- MI (prevents LV remodeling)
- Hypertension
- HF
- EF <40%