Drug Synergy Flashcards
What is atripla
comprises of three drugs efavirenz (NNRTI), tenofovir (NtRTI) and entricibatine (NRTI) that are used in HAART therapy to treat HIV
What is a CCR5 inhibitor
Maraviroc
What is a gp41 inhibitor
Enfuvirtide
What are two integrase inhibitors
Raltegravir and Elvitegravir
What are drugs are used in combination to treat Hep C
Sofosbuvir, PEG interferon and Ribavarin
Two antibiotics that act together to promote increased death of Staph and enterococcus
Gentamicin/Aminoglycoside and penicillin
two drugs used together to restrict fungal growth
Flucytosine and amphotericin
Two drugs used together to inhibit the DNA synthesis pathway
Trimethoprim and Sulfonamides
Two drugs used to inhibit Prostate cancer
Cisplatin and etoposide
Immunsuppressants used in synergy
Glucocorticoids, cytotoxic drugs, calcineuron inhibitors, and antibody therapy targetted towards inhibiting cytokine receptors, t-lymphocyte depletion and co-stimulation block
What antibody is an anti-IL-2R
Daclizumab
What antibody is targetted against T cells
Anti-thymocyte globulin
What Fusion protein is against Co-stimulation of APCs
Abatacept (CTLA-4fusion)
What HIV drugs as NNRTI
Zalovudine (AZT) and Zalcitabine