Drug Suffixes Flashcards

1
Q

-conazole

A

Antifungal (ketoconazole, fluconazole)

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2
Q

-cillin

A

Penicillin (methicillin)

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3
Q

-cycline

A

Antibiotic, protein synthesis inhibitor (tetracycline)

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4
Q

-navir

A

Protease inhibitor, for HIV (saquinavir, ritonavir)

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5
Q

-triptan

A

5-HT agonists, for migraine (sumatriptan, rizatriptan)

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6
Q

-ane

A

Inhalational general anesthetic (halothane, isoflurane)

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7
Q

-caine

A

Local anesthetic (lidocaine)

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8
Q

-operidol

A

Butyrophenone, neuroleptic (haloperidol)

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9
Q

-azine

A

Phenothiazine, neuroleptic (chlorpromazine, thioridazine), antiemetic (promethazine)

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10
Q

-barbital

A

Barbiturate (phenobarbital)

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11
Q

-zolam

A

Benzodiazepine (alprazolam)

Also “-azepam”

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12
Q

-azepam

A

Benzodiazepine (diazepam, lorazepam)

Also “-zolam”

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13
Q

-etine

A

SSRI (fluoxetine, paroxetine, sertraline)

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14
Q

-ipramine

A

TCA (impiramine, clomipramine)

Also “-triptyline”

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15
Q

-triptyline

A

TCA (amitrtiptyline, nortriptyline)

Also “-ipramine”

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16
Q

-olol

A

ß-antagonist (propranolol, atenolol, metoprolol)

“-ilol” and “-alol” are mixed alpha and ß blockers
carvedILOL and labetALOL

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17
Q

-terol

A

ß2-agonist (albuterol, salmeterol)

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18
Q

-zosin

A

α1-agonist (prazosin, doxazosin)

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19
Q

-oxin

A

Cardiac glycoside (digoxin)

20
Q

-pril

A

ACE-inhibitor (captopril, lisinopril)

21
Q

-afil

A

PDE inhibitor, erectile dysfunction (sildenafil, tadalafil)

22
Q

-tropin

A

Pituitary hormone (somatotropin, thyrotropin (TSH))

23
Q

-tidine

A

H2 antagonist (cimetidine, ranitidine)

24
Q

-chol

A

Muscarinic/cholinergic agonist (bethanechol, carbachol)

25
Q

-bendazole

A

Worm/helminth infections (mebendazole, albendazole)

26
Q

-curium

A

Non-depolarizing neuromuscular blocker (atracurium)

Also “-curonium”

27
Q

-curonium

A

Non-depolarizing neuromuscular blocker (vecuronium)

Also “-curium”

28
Q

-dipine

A

Dihydropyradine CCB (nifedipine, amlodipine)

29
Q

-dronate

A

Bisphosphonate (alendronate, risedronate)

30
Q

-gliptin

A

DPP-IV inhibitors, for T2DM (sitagliptin, saxagliptin)

31
Q

-glitazone

A

Thiazolidinediones, for T2DM (pioglitazone, rosiglitazone)

32
Q

-mab

A

Monoclonal antibody (infliximab, rituximab)

33
Q

-mustine

A

Nitrosourea, for brain cancer, crosses BBB (lomustine)

34
Q

-phylline

A

Methylxanthine (theophylline, aminophylline)

35
Q

-prost

A

Prostoglandin analog (latanoprost, travoprost)

36
Q

-sartan

A

Angiotensin receptor blocker, ARB (losartan, valsartan)

37
Q

-statin

A

HMG-CoA reductase inhibitor (atorvastatin, simvastatin)

38
Q

-stigmine

A

Anticholinesterase (neostigmine, physostigmine, rivastigmine (for Alzheimer’s))

39
Q

-adine

A

2nd generation H2 blocker (loratadine, fexofenadine)

Less BBB penetration than first generation H1 blockers –> less sedation

40
Q
  • en/-ine

- en/-ate

A

1st generation H1 blocker (diphenhydramine, dimenhyrinate)

BBB penetration –> sedation

41
Q

-lukast

A

Leukotriene receptor inhibitors (montelukast, zafirlukast)

Blocks chemotaxis of neutrophils (for asthma)

42
Q

-asone

A

Corticosteroids (beclomethasone, fluticasone)

43
Q

-dipine

A

Calcium channel blocker (nifedipine, amlodipine)

44
Q

-azine

A

Typical antipsychotics (trifluoperazine, fluphenazine, chlorpromazine, thioridazine)

Also, haloperidol

45
Q

-ilide

A

K+ channel blockers - class III antiarrhythmics (ibutilide, dofetilide)

Also, amiodarone and sotalol

46
Q

-capone

A

COMT inhibitor for add on Parkinson therapy (entacapone, tolcapone)